Phenotype Help

AIM4 / YBR194W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
Non-essential gene; null mutant displays altered competitive fitness in a variety of media, and a decreased growth rate in rich medium; null mutant has a reduced ability to utilize the nitrogen sources, glutamate and proline; null mutant has a reduced frequency of spontaneous mitochondrial genome loss; null mutant has an abnormally elongated bud, and has decreased resistance to oxidative stress, UV treatment, desiccation, freeze-thaw and is heat sensitive

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

51 entries for 18 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
bud morphology: abnormal
systematic mutation setnull
Allele: aim4-Δ
S288CDetails: bud is abnormally elongated
Watanabe M, et al. (2009) PMID:19466415
chemical compound accumulation: decreased
homozygous diploid, systematic mutation set

glycogen accumulation in diploid mutant strains grown in microtiter plates

null
Allele: aim4-Δ
S288C glycogenWilson WA, et al. (2002) PMID:12096123
competitive fitness: decreased
homozygous diploid, competitive growth

genome-wide fitness profiling

null
Allele: aim4-Δ
S288CMedia: YPD
Details: Relative fitness score: 0.854
Deutschbauer AM, et al. (2005) PMID:15716499
competitive fitness: decreased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: aim4-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 0.45
Breslow DK, et al. (2008) PMID:18622397
competitive fitness: decreased
systematic mutation setnull
Allele: aim4-Δ
S288CMedia: glycerol medium, YPG
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: aim4-Δ
S288CMedia: rich medium (YPD) w/6% ethanol, ETH
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: aim4-Δ
S288CMedia: synthetic complete medium, SC
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: aim4-Δ
S288CMedia: synthetic oak exudate medium, OAK
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: aim4-Δ
S288CMedia: YPD
Qian W, et al. (2012) PMID:23103169
competitive fitness: increased
homozygous diploid, competitive growthnull
Allele: aim4-Δ
S288CTreatment: conditions that mimic Phase I of a batch fermentation, equivalent to ~14 hours after inoculation of a batch fermentation
Novo M, et al. (2013) PMID:24040173
Showing 1 to 10 of 51 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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