APE3 / YBR286W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; null mutant displays decreased resistance to heat and decreased competitive fitness in both minimal medium and rich medium with 6% ethanol; null mutant displays decreased telomere length and decreased chronological lifespan; null mutant has decreased resistance to several different toxins; heterozygous diploid null is haploinsufficient in turbidostat grown cells in FPM medium but is haploproficient in conditions that mimic phase I of batch fermentation; overexpression results in decreased vegetative growth

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources