STP22 / YCL008C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

STP22/YCL008C is a non-essential gene; null mutants are viable but exhibit a range of phenotypic changes including decreased acquired thermotolerance, decreased biofilm formation, decreased duration of cell cycle progression in the G2 phase, increased chemical compound accumulation, decreased endocytosis, altered metal resistance, absent or decreased protein secretion, abnormal subcellular morphology, decreased toxin resistance, absent utilization of carbon sources, absent vacuolar transport, decreased acid pH resistance, abnormal colony appearance, altered competitive fitness, decreased desiccation resistance, increased heat sensitivity, decreased hyperosmotic stress resistance, decreased innate thermotolerance, decreased oxidative stress resistance, decreased respiratory growth rate, decreased RNA accumulation, decreased sporulation efficiency, decreased stress resistance, decreased telomere length, decreased transposable element transposition, decreased utilization rate of nitrogen sources, abnormal vacuolar morphology, and decreased vegetative growth rate. Repressible mutants show decreased vacuolar transport, while reduction of function mutants exhibit abnormal vacuolar transport. Overexpression of STP22 results in decreased resistance to chemicals, abnormal vacuolar morphology, and decreased vegetative growth rate.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources