Phenotype Help

HSP30 / YCR021C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

18 entries for 15 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
acid pH resistance: decreased
classical geneticsnull
Allele: hsp30-Δ
Other sorbic acidMedia: low pH, pH 3.8
Chattopadhyay S, et al. (2000) PMID:11053386
auxotrophy
homozygous diploid, systematic mutation setnull
Allele: hsp30-Δ
S288C myo-inositolVilla-García MJ, et al. (2011) PMID:21136082
competitive fitness: increased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: hsp30-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 1.006
Breslow DK, et al. (2008) PMID:18622397
desiccation resistance: decreased
systematic mutation setnull
Allele: hsp30-Δ
S288CDetails: less than 10% viability after dehydration stress
Rodríguez-Porrata B, et al. (2012) PMID:22181064
haploinsufficient
heterozygous diploid, competitive growth

genome-wide fitness profiling

null
Allele: hsp30-Δ
S288CMedia: turbidostat growth in FPM medium
Details: Relative growth score: -0.0036
Pir P, et al. (2012) PMID:22244311
heat sensitivity: decreased
systematic mutation set

high throughput heat ramp cell death assay

null
Allele: hsp30-Δ
S288CTemperature: elevated temperature
Details: ramp temperature from ambient to 30 deg C immediately, hold 1 min at 30 deg C, ramp temperature from 30 deg C to 62 deg C over 20 min, return to ambient
Teng X, et al. (2011) PMID:21814286
heat sensitivity: increased
classical geneticsnull
Allele: hsp30-Δ
S288C200 ug/ml 2-deoxy-D-glucoseTemperature: elevated temperature, 50 °C
Meena RC, et al. (2011)
lifespan: increased
systematic mutation setnull
Allele: hsp30-Δ
S288CMedia: cells stored on YPD plates at 4 deg C for 5 years
Details: hibernating lifespan extended
Postma L, et al. (2009) PMID:20157578
protein activity: increased
Reporter: Pma1p
classical geneticsnull
Allele: hsp30-Δ
OtherDetails: displays enhanced increases in plasma membrane H+-ATPase (Pma1p) activity with either heat shock or weak organic acid stress
Piper PW, et al. (1997) PMID:9250391
resistance to chemicals: decreased
classical geneticsnull
Allele: hsp30-Δ
S288C12% ethanolYang J, et al. (2011) PMID:21437883
Showing 1 to 10 of 18 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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