ELO2 / YCR034W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

ELO2/YCR034W is a non-essential gene; null mutants are viable and show increased heat sensitivity, decreased mating efficiency and response, absent pheromone-induced cell cycle arrest, delayed shmoo formation, and decreased toxin resistance. They also display abnormal bud morphology and budding patterns, decreased alkaline pH resistance, decreased chronological lifespan, decreased desiccation resistance, decreased respiratory growth, decreased sporulation, and decreased vegetative growth. Null mutants have abnormal endoplasmic reticulum and lipid particle morphology, increased killer toxin resistance, and increased metal resistance. Reduction of function mutants exhibit increased heat sensitivity, while overexpression mutants show decreased acid pH resistance, decreased heat sensitivity, and decreased vegetative growth.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources