PAT1 / YCR077C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

PAT1/YCR077C is a non-essential gene; null mutants are viable and show increased apoptosis and cell size, normal chitin deposition, and increased cold sensitivity and colony sectoring. Null mutants also exhibit decreased competitive fitness, desiccation resistance, fermentative growth rate, heat sensitivity, metal resistance, replicative lifespan, respiratory growth, sporulation, toxin resistance, vegetative growth rate, and overall viability. Additionally, null mutants show abnormal nuclear and subcellular morphology, but increased stress resistance. Overexpression of PAT1 results in decreased vegetative growth.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources