VMA3 / YEL027W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

VMA3/YEL027W is a non-essential gene; null mutants are viable but exhibit a range of phenotypic changes including altered chemical compound accumulation, decreased metal resistance, decreased oxidative stress resistance, increased protein/peptide accumulation, abnormal protein/peptide distribution, decreased resistance to chemicals, absent respiratory growth, decreased small molecule transport, decreased vegetative growth rate, decreased alkaline pH resistance, auxotrophy, abnormal budding pattern, increased duration of cell cycle progression in the G1 phase, abnormal cell shape, decreased chronological lifespan, decreased competitive fitness, decreased desiccation resistance, decreased freeze-thaw resistance, increased heat sensitivity, decreased hyperosmotic stress resistance, abnormal mitochondrial morphology, increased mitophagy, decreased protein/peptide modification, decreased resistance to enzymatic treatment, altered toxin resistance, decreased utilization rates of carbon and iron sources, and decreased vegetative growth. Overexpression of VMA3 results in decreased vegetative growth.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources