Phenotype Help

CEM1 / YER061C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
Non-essential gene; null mutant is incapable of respiratory growth (on non-fermentable carbon sources, such as glycerol, ethanol, lactate), shows a slow growth rate on a fermentable carbon source (glucose) and sensitivity to oxidative stress, cell-wall and DNA damaging agents and lipids; null mutation reduces the number of lipid droplets

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

54 entries for 20 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
chemical compound accumulation: abnormal
systematic mutation setnull
Allele: cem1-Δ
S288C alpha-amino acidDetails: Significantly altered free amino acid profile (X^2- test adjusted p < 0.01), showing 11 simultaneous amino acid changes (Z-test, adjusted p < 0.01)
Mülleder M, et al. (2016) PMID:27693354
chemical compound accumulation: decreased
systematic mutation setnull
Allele: cem1-Δ
S288C methionineMülleder M, et al. (2016) PMID:27693354
chemical compound accumulation: decreased
systematic mutation setnull
Allele: cem1-Δ
S288C serineMülleder M, et al. (2016) PMID:27693354
chemical compound accumulation: decreased
systematic mutation setnull
Allele: cem1-Δ
S288C leucineMülleder M, et al. (2016) PMID:27693354
chemical compound accumulation: decreased
systematic mutation setnull
Allele: cem1-Δ
S288C prolineMülleder M, et al. (2016) PMID:27693354
chemical compound accumulation: decreased
systematic mutation setnull
Allele: cem1-Δ
S288C glutamineMülleder M, et al. (2016) PMID:27693354
chemical compound accumulation: increased
homozygous diploidnull
Allele: cem1-Δ
S288C0.1 mM potassium tellurite, tellurium atomOttosson LG, et al. (2010) PMID:20675578
chemical compound accumulation: increased
systematic mutation setnull
Allele: cem1-Δ
S288C tyrosineMülleder M, et al. (2016) PMID:27693354
chemical compound accumulation: increased
systematic mutation setnull
Allele: cem1-Δ
S288C lysineMülleder M, et al. (2016) PMID:27693354
chemical compound accumulation: increased
systematic mutation setnull
Allele: cem1-Δ
S288C alanineMülleder M, et al. (2016) PMID:27693354
Showing 1 to 10 of 54 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


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Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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