SLT2 / YHR030C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

SLT2/YHR030C is a non-essential gene; null mutants are viable but exhibit a wide range of phenotypic changes including decreased acid and alkaline pH resistance, abnormal cell wall morphology, decreased chronological lifespan, increased cold and heat sensitivity, decreased hydrostatic pressure resistance, decreased killer toxin and metal resistance, decreased mitophagy, decreased osmotic and oxidative stress resistance, absent pexophagy, decreased resistance to enzymatic treatment, abnormal RNA accumulation, increased toxin resistance, decreased biofilm formation, decreased cell size, decreased chitin deposition, decreased competitive fitness, decreased desiccation resistance, decreased endocytosis, decreased mating response, decreased prion formation, decreased respiratory growth, decreased stress resistance, decreased utilization of nitrogen sources, abnormal vacuolar morphology, and decreased rate of vegetative growth. Reduction of function mutants exhibit abnormal cell wall morphology, increased heat sensitivity, and decreased metal resistance. Conditional mutants show increased heat sensitivity, decreased hyperosmotic stress resistance, absent respiratory growth, and decreased toxin resistance. Repressible mutants display decreased toxin resistance.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources