Literature Help
BRL1 / YHR036W Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Kralt A, et al. (2022) An amphipathic helix in Brl1 is required for nuclear pore complex biogenesis in S. cerevisiae. Elife 11 PMID:36000978
- Ravoitytė B, et al. (2022) Adaptive Response of Saccharomyces Hosts to Totiviridae L-A dsRNA Viruses Is Achieved through Intrinsically Balanced Action of Targeted Transcription Factors. J Fungi (Basel) 8(4) PMID:35448612
- Vitale J, et al. (2022) A perinuclear α-helix with amphipathic features in Brl1 promotes NPC assembly. Mol Biol Cell 33(5):ar35 PMID:35293775
- Rempel IL, et al. (2019) Age-dependent deterioration of nuclear pore assembly in mitotic cells decreases transport dynamics. Elife 8 PMID:31157618
- Vallotton P, et al. (2019) Mapping the native organization of the yeast nuclear pore complex using nuclear radial intensity measurements. Proc Natl Acad Sci U S A 116(29):14606-14613 PMID:31262825
- Segovia R, et al. (2017) Genome-wide bisulfite sensitivity profiling of yeast suggests bisulfite inhibits transcription. Mutat Res Genet Toxicol Environ Mutagen 821:13-19 PMID:28735739
- Paul B and Montpetit B (2016) Altered RNA processing and export lead to retention of mRNAs near transcription sites and nuclear pore complexes or within the nucleolus. Mol Biol Cell 27(17):2742-56 PMID:27385342
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Liu G, et al. (2015) Gene Essentiality Is a Quantitative Property Linked to Cellular Evolvability. Cell 163(6):1388-99 PMID:26627736
- Lone MA, et al. (2015) Yeast Integral Membrane Proteins Apq12, Brl1, and Brr6 Form a Complex Important for Regulation of Membrane Homeostasis and Nuclear Pore Complex Biogenesis. Eukaryot Cell 14(12):1217-27 PMID:26432634
- Wu J, et al. (2015) Genome-wide screen uncovers novel pathways for tRNA processing and nuclear-cytoplasmic dynamics. Genes Dev 29(24):2633-44 PMID:26680305
- Lo Presti L, et al. (2009) Choice of an adequate promoter for efficient complementation in Saccharomyces cerevisiae: a case study. Res Microbiol 160(6):380-8 PMID:19589384
- Lo Presti L, et al. (2007) Functional characterization of Pneumocystis carinii brl1 by transspecies complementation analysis. Eukaryot Cell 6(12):2448-52 PMID:17993570
- Saitoh YH, et al. (2005) Brl1p -- a novel nuclear envelope protein required for nuclear transport. Traffic 6(6):502-17 PMID:15882446
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
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Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Gardner JM, et al. (2021) A mutation in budding yeast BRR6 affecting nuclear envelope insertion of the spindle pole body. MicroPubl Biol 2021 PMID:34549174
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Garapati HS and Mishra K (2018) Comparative genomics of nuclear envelope proteins. BMC Genomics 19(1):823 PMID:30445911
- Vincent M, et al. (2014) Surveying the floodgates: estimating protein flux into the endoplasmic reticulum lumen in Saccharomyces cerevisiae. Front Physiol 5:444 PMID:25431559
- Waern K and Snyder M (2013) Extensive transcript diversity and novel upstream open reading frame regulation in yeast. G3 (Bethesda) 3(2):343-52 PMID:23390610
- Guirola M, et al. (2010) Lack of DNA helicase Pif1 disrupts zinc and iron homoeostasis in yeast. Biochem J 432(3):595-605 PMID:20858222
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Del Vescovo V, et al. (2008) Role of Hog1 and Yaf9 in the transcriptional response of Saccharomyces cerevisiae to cesium chloride. Physiol Genomics 33(1):110-20 PMID:18198280
- Millson SH, et al. (2005) A two-hybrid screen of the yeast proteome for Hsp90 interactors uncovers a novel Hsp90 chaperone requirement in the activity of a stress-activated mitogen-activated protein kinase, Slt2p (Mpk1p). Eukaryot Cell 4(5):849-60 PMID:15879519
- Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 PMID:14562095
Reviews
No reviews curated.
Download References (.nbib)
- Kobaisi F, et al. (2020) High-throughput synthetic rescue for exhaustive characterization of suppressor mutations in human genes. Cell Mol Life Sci 77(21):4209-4222 PMID:32270227
- Rüthnick D and Schiebel E (2018) Duplication and Nuclear Envelope Insertion of the Yeast Microtubule Organizing Centre, the Spindle Pole Body. Cells 7(5) PMID:29748517
- Jaspersen SL and Ghosh S (2012) Nuclear envelope insertion of spindle pole bodies and nuclear pore complexes. Nucleus 3(3):226-36 PMID:22572959
- Schneiter R and Cole CN (2010) Integrating complex functions: coordination of nuclear pore complex assembly and membrane expansion of the nuclear envelope requires a family of integral membrane proteins. Nucleus 1(5):387-92 PMID:21326820
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Download References (.nbib)
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Lone MA, et al. (2015) Yeast Integral Membrane Proteins Apq12, Brl1, and Brr6 Form a Complex Important for Regulation of Membrane Homeostasis and Nuclear Pore Complex Biogenesis. Eukaryot Cell 14(12):1217-27 PMID:26432634
- Saitoh YH, et al. (2005) Brl1p -- a novel nuclear envelope protein required for nuclear transport. Traffic 6(6):502-17 PMID:15882446
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Download References (.nbib)
- Vitale J, et al. (2022) A perinuclear α-helix with amphipathic features in Brl1 promotes NPC assembly. Mol Biol Cell 33(5):ar35 PMID:35293775
- Lone MA, et al. (2015) Yeast Integral Membrane Proteins Apq12, Brl1, and Brr6 Form a Complex Important for Regulation of Membrane Homeostasis and Nuclear Pore Complex Biogenesis. Eukaryot Cell 14(12):1217-27 PMID:26432634
- Saitoh YH, et al. (2005) Brl1p -- a novel nuclear envelope protein required for nuclear transport. Traffic 6(6):502-17 PMID:15882446
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- Michaelis AC, et al. (2023) The social and structural architecture of the yeast protein interactome. Nature 624(7990):192-200 PMID:37968396
- Mishra PK, et al. (2023) Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability. Mol Biol Cell 34(10):ar99 PMID:37436802
- Kralt A, et al. (2022) An amphipathic helix in Brl1 is required for nuclear pore complex biogenesis in S. cerevisiae. Elife 11 PMID:36000978
- Lamb NA, et al. (2022) Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes. Genetics 221(4) PMID:35686905
- Zhang W, et al. (2021) A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis. Open Biol 11(11):210250 PMID:34814743
- Au WC, et al. (2020) Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast. PLoS Genet 16(2):e1008597 PMID:32032354
- Sanders E, et al. (2020) Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1. G3 (Bethesda) 10(12):4359-4368 PMID:33115720
- van Leeuwen J, et al. (2020) Systematic analysis of bypass suppression of essential genes. Mol Syst Biol 16(9):e9828 PMID:32939983
- Kuzmin E, et al. (2018) Systematic analysis of complex genetic interactions. Science 360(6386) PMID:29674565
- Miller JE, et al. (2018) Genome-Wide Mapping of Decay Factor-mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4. G3 (Bethesda) 8(1):315-330 PMID:29158339
- Mount HO, et al. (2018) Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs. PLoS Genet 14(4):e1007319 PMID:29702647
- Zhang W, et al. (2018) Brr6 and Brl1 locate to nuclear pore complex assembly sites to promote their biogenesis. J Cell Biol 217(3):877-894 PMID:29439116
- Lapointe CP, et al. (2017) Architecture and dynamics of overlapped RNA regulatory networks. RNA 23(11):1636-1647 PMID:28768715
- Zander G, et al. (2017) Saccharomyces cerevisiae Gle2/Rae1 is involved in septin organization, essential for cell cycle progression. Yeast 34(11):459-470 PMID:28776765
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Kershaw CJ, et al. (2015) Integrated multi-omics analyses reveal the pleiotropic nature of the control of gene expression by Puf3p. Sci Rep 5:15518 PMID:26493364
- Liu G, et al. (2015) Gene Essentiality Is a Quantitative Property Linked to Cellular Evolvability. Cell 163(6):1388-99 PMID:26627736
- Lone MA, et al. (2015) Yeast Integral Membrane Proteins Apq12, Brl1, and Brr6 Form a Complex Important for Regulation of Membrane Homeostasis and Nuclear Pore Complex Biogenesis. Eukaryot Cell 14(12):1217-27 PMID:26432634
- van Pel DM, et al. (2013) Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork. G3 (Bethesda) 3(2):273-82 PMID:23390603
- Douglas AC, et al. (2012) Functional analysis with a barcoder yeast gene overexpression system. G3 (Bethesda) 2(10):1279-89 PMID:23050238
- Stirling PC, et al. (2011) The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components. PLoS Genet 7(4):e1002057 PMID:21552543
- Michelot A, et al. (2010) Reconstitution and protein composition analysis of endocytic actin patches. Curr Biol 20(21):1890-9 PMID:21035341
- Hasegawa Y, et al. (2008) Distinct roles for Khd1p in the localization and expression of bud-localized mRNAs in yeast. RNA 14(11):2333-47 PMID:18805955
- Yu H, et al. (2008) High-quality binary protein interaction map of the yeast interactome network. Science 322(5898):104-10 PMID:18719252
- Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43 PMID:16554755
- Saitoh YH, et al. (2005) Brl1p -- a novel nuclear envelope protein required for nuclear transport. Traffic 6(6):502-17 PMID:15882446
- Chan TF, et al. (2000) A chemical genomics approach toward understanding the global functions of the target of rapamycin protein (TOR). Proc Natl Acad Sci U S A 97(24):13227-32 PMID:11078525
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
Download References (.nbib)
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Zhou X, et al. (2021) Cross-compartment signal propagation in the mitotic exit network. Elife 10 PMID:33481703
- MacGilvray ME, et al. (2020) Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses. J Proteome Res 19(8):3405-3417 PMID:32597660
- Swaney DL, et al. (2013) Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nat Methods 10(7):676-82 PMID:23749301
- Holt LJ, et al. (2009) Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution. Science 325(5948):1682-6 PMID:19779198
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Songdech P, et al. (2024) Increased production of isobutanol from xylose through metabolic engineering of Saccharomyces cerevisiae overexpressing transcription factor Znf1 and exogenous genes. FEMS Yeast Res 24 PMID:38331422
- Forster DT, et al. (2022) BIONIC: biological network integration using convolutions. Nat Methods 19(10):1250-1261 PMID:36192463
- Nicastro R, et al. (2021) Indole-3-acetic acid is a physiological inhibitor of TORC1 in yeast. PLoS Genet 17(3):e1009414 PMID:33690632
- Ohnuki S and Ohya Y (2018) High-dimensional single-cell phenotyping reveals extensive haploinsufficiency. PLoS Biol 16(5):e2005130 PMID:29768403
- Khurana V, et al. (2017) Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways. Cell Syst 4(2):157-170.e14 PMID:28131822
- Fröhlich F, et al. (2015) The GARP complex is required for cellular sphingolipid homeostasis. Elife 4 PMID:26357016
- Huang Z, et al. (2013) A functional variomics tool for discovering drug-resistance genes and drug targets. Cell Rep 3(2):577-85 PMID:23416056
- Neumüller RA, et al. (2013) Conserved regulators of nucleolar size revealed by global phenotypic analyses. Sci Signal 6(289):ra70 PMID:23962978
- Shively CA, et al. (2013) Genetic networks inducing invasive growth in Saccharomyces cerevisiae identified through systematic genome-wide overexpression. Genetics 193(4):1297-310 PMID:23410832
- van Pel DM, et al. (2013) Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork. G3 (Bethesda) 3(2):273-82 PMID:23390603
- Armakola M, et al. (2012) Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. Nat Genet 44(12):1302-9 PMID:23104007
- Stirling PC, et al. (2011) The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components. PLoS Genet 7(4):e1002057 PMID:21552543
- Svensson JP, et al. (2011) Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance. BMC Syst Biol 5:157 PMID:21978764
- Venters BJ, et al. (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92 PMID:21329885
- Holt LJ, et al. (2009) Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution. Science 325(5948):1682-6 PMID:19779198
- Ben-Aroya S, et al. (2008) Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae. Mol Cell 30(2):248-58 PMID:18439903
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Sinha H, et al. (2008) Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast. Genetics 180(3):1661-70 PMID:18780730
- MacIsaac KD, et al. (2006) An improved map of conserved regulatory sites for Saccharomyces cerevisiae. BMC Bioinformatics 7:113 PMID:16522208
- Yu L, et al. (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47 PMID:16943325
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549