VMA22 / YHR060W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

VMA22/YHR060W is a non-essential gene; null mutants are viable but exhibit a wide range of phenotypic changes including decreased metal resistance, increased protein/peptide accumulation, decreased resistance to chemicals, abnormal vacuolar morphology, decreased acid and alkaline pH resistance, auxotrophy, increased duration of cell cycle progression in the G1 phase, decreased chronological lifespan, decreased competitive fitness, increased heat sensitivity, abnormal lipid particle morphology, abnormal mitochondrial morphology, decreased oxidative stress resistance, decreased resistance to enzymatic treatment, absent respiratory growth, increased toxin resistance, decreased utilization of carbon and iron sources, and decreased vegetative growth.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources