Phenotype Help

KOG1 / YHR186C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

21 entries for 8 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
cell cycle progression in G1 phase: arrested
classical geneticsconditional
Allele: kog1-1
S288CTemperature: elevated temperature, 37 °C
Stirling PC, et al. (2011) PMID:21552543
competitive fitness: increased
competitive growth

fitness profiling of essential genes using hypomorphic DAmP alleles

reduction of functionS288CMedia: minimal medium
Details: Relative fitness score: 1.002
Breslow DK, et al. (2008) PMID:18622397
haploinsufficient
heterozygous diploid, systematic mutation setnull
Allele: kog1-Δ
S288C NVP-BHS345Shimada K, et al. (2013) PMID:24035500
inviable
classical geneticsnull
Allele: kog1-Δ
OtherLoewith R, et al. (2002) PMID:12408816
inviable
systematic mutation setnull
Allele: kog1-Δ
S288CGiaever G, et al. (2002) PMID:12140549
protein/peptide distribution: abnormal
Reporter: Gat1p-GFP
classical geneticsconditional
Allele: kog1-1
S288CMedia: nutrient-rich medium
Temperature: elevated temperature, 37 °C
Details: precocious nuclear localization under nutrient-rich conditions
Stirling PC, et al. (2011) PMID:21552543
resistance to chemicals: decreased
classical geneticsunspecifiedW3032 mM tetracaineAraki T, et al. (2005) PMID:16394584
resistance to chemicals: decreased
heterozygous diploid, systematic mutation setnull
Allele: kog1-Δ
Other sirolimusDetails: sirolimus is rapamycin
Xie MW, et al. (2005) PMID:15883373
resistance to chemicals: decreased
heterozygous diploid, systematic mutation setnull
Allele: kog1-Δ
S288C caffeineHoepfner D, et al. (2014) PMID:24360837
resistance to chemicals: decreased
heterozygous diploid, systematic mutation setnull
Allele: kog1-Δ
S288C everolimusHoepfner D, et al. (2014) PMID:24360837
Showing 1 to 10 of 21 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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