AIM19 / YIL087C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; null mutant displays increased competitive fitness in minimal medium, rich medium, and medium containing a non-fermentable carbon source, yet paradoxically has been reported to have a decreased growth rate on medium containing either a fermentable or non-fermentable carbon source; null mutant displays decreased resistance to both hyperosmotic and oxidative stress; null mutant is inhibited by palmitoleic acid; null mutant is deficient in glycogen accumulation; heterozygous null mutant is haploproficient; overexpression results in a decreased growth rate and an increase in the proportion of cells with a 1N DNA content, indicative of a G1 arrest or delay

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources