Phenotype Help

PRM5 / YIL117C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

18 entries for 12 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
chemical compound accumulation: abnormal
systematic mutation setnull
Allele: prm5-Δ
S288C alpha-amino acidDetails: Significantly altered free amino acid profile (X^2- test p < 0.01), showing 1 simultaneous amino acid change (Z-test, adjusted p < 0.01)
Mülleder M, et al. (2016) PMID:27693354
chemical compound accumulation: decreased
systematic mutation setnull
Allele: prm5-Δ
S288C methionineMülleder M, et al. (2016) PMID:27693354
competitive fitness: decreased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: prm5-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 0.994
Breslow DK, et al. (2008) PMID:18622397
competitive fitness: increased
systematic mutation setnull
Allele: prm5-Δ
S288CMedia: glycerol medium, YPG
Qian W, et al. (2012) PMID:23103169
filamentous growth: increased
systematic mutation setoverexpressionSigma1278bJin R, et al. (2008) PMID:17989363
oxidative stress resistance: decreased
homozygous diploid, competitive growthnull
Allele: prm5-Δ
S288C3 mM hydrogen peroxideBrown JA, et al. (2006) PMID:16738548
resistance to chemicals: decreased
systematic mutation set

genome-wide ethanol tolerance screening of the systematic deletion set

null
Allele: prm5-Δ
S288C8% ethanolTeixeira MC, et al. (2009) PMID:19633105
resistance to chemicals: decreased
heterozygous diploid, systematic mutation setnull
Allele: prm5-Δ
S288Cderivative myriocinHoepfner D, et al. (2014) PMID:24360837
resistance to chemicals: decreased
heterozygous diploid, systematic mutation setnull
Allele: prm5-Δ
S288C nigericinHoepfner D, et al. (2014) PMID:24360837
resistance to chemicals: decreased
heterozygous diploid, systematic mutation setnull
Allele: prm5-Δ
S288C valinomycinHoepfner D, et al. (2014) PMID:24360837
Showing 1 to 10 of 18 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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