MGA2 / YIR033W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

MGA2/YIR033W is a non-essential gene; null mutants are viable and exhibit decreased alkaline pH resistance, anaerobic growth, competitive fitness, innate thermotolerance, replicative lifespan, utilization rates of carbon and nitrogen sources, and vegetative growth. These mutants also show delayed cell cycle progression through the G2/M phase transition, increased heat sensitivity, increased oxidative stress resistance, increased respiratory growth, and abnormal vacuolar morphology. Overexpression of MGA2 results in decreased competitive fitness, metal resistance, vegetative growth rate, and viability.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources