Phenotype Help

IRC6 / YFR043C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

11 entries for 9 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
competitive fitness: decreased
systematic mutation setnull
Allele: irc6-Δ
S288C ethanolQian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: irc6-Δ
S288CMedia: glycerol medium, YPG
Qian W, et al. (2012) PMID:23103169
competitive fitness: increased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: irc6-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 1.005
Breslow DK, et al. (2008) PMID:18622397
heat sensitivity: decreased
systematic mutation set

high throughput heat ramp cell death assay

null
Allele: irc6-Δ
S288CTemperature: elevated temperature
Details: ramp temperature from ambient to 30 deg C immediately, hold 1 min at 30 deg C, ramp temperature from 30 deg C to 62 deg C over 20 min, return to ambient
Teng X, et al. (2011) PMID:21814286
killer toxin resistance: increased
systematic mutation setnull
Allele: irc6-Δ
S288CDetails: K2
Servienė E, et al. (2012) PMID:23227207
killer toxin resistance: increased
systematic mutation setnull
Allele: irc6-Δ
S288CDetails: K28 killer toxin
Carroll SY, et al. (2009) PMID:19853568
killer toxin resistance: normal
classical geneticsnull
Allele: irc6-Δ
SEY6210Details: K28 killer toxin
Gorynia S, et al. (2012) PMID:22993212
oxidative stress resistance: increased
homozygous diploid, competitive growthnull
Allele: irc6-Δ
S288C3 mM hydrogen peroxideBrown JA, et al. (2006) PMID:16738548
protein/peptide accumulation: increased
Reporter: Rad52-YFP

Rad52-YFP foci formation

homozygous diploid, large-scale surveynull
Allele: irc6-Δ
W303Alvaro D, et al. (2007) PMID:18085829
vacuolar morphology: abnormal
systematic mutation set

screen all non-essential genes for inability to fragment vacuoles in response to salt addition

null
Allele: irc6-Δ
S288C0.4 M sodium chlorideDetails: small defect in vacuolar fragmentation
Michaillat L and Mayer A (2013) PMID:23383298
Showing 1 to 10 of 11 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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