ARP2 / YDL029W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Essential/non-essential gene; null mutant has been reported to be either viable and slow growing or inviable in S288C; conditional mutant arrests non-uniformly and loses viability; conditional mutant displays abnormal actin cytoskeleton morphology, abnormal bud morphology, a random budding pattern in both haploids and diploids, abnormal chitin deposition, defective endocytosis and sensitivity to hyperosmotic stress; conditional mutant displays decreased mitochondrial movement velocity, loss of directed movement, and abnormal mitochondrial morphology; homozygous conditional diploid has a defect in spore wall formation and a severe sporulation defect; hypomorphic DAmP allele has reduced telomere length

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources