SIT4 / YDL047W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; null mutant has fermentative and respiratory growth defects, increased heat sensitivity, abnormally elongated buds, extended chronological lifespan, decreased telomere length, and increased multidrug and toxin sensitivity; null mutants have semi-smooth colony morphology, altered mitochondrial morphology, a vacuolar fragmentation defect, decreased lipid droplet size, content and quantity and are sensitive to hyperosmotic stress; conditional mutant has an actin depolarization defect, is resistant to oxidants, and contains elevated levels of glutathione

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources