MAF1 / YDR005C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; null mutant displays a decreased growth rate, decreased utilization of glutamate, ribose, and is unable to grow on glycerol at elevated temperature; null mutant accumulates tRNA relative to total RNA and shows decreased silencing at tRNA genes adjacent to strong RNA pol II promoters; null mutant displays decreased biofilm formation; overexpression results in decreased vegetative growth, decreased filamentous growth and is unable to invade agar; diploid null displays decreased sporulation efficiency

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources