Phenotype Help

SED1 / YDR077W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

25 entries for 14 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
chromosome/plasmid maintenance: decreased
heterozygous diploid, systematic mutation setnull
Allele: sed1-Δ
S288CAssay: diploid bimater (BiM) assay
Details: haploinsufficiency results in chromosome instability (CIN); scored >= 2 standard deviations above the mean
Choy JS, et al. (2013) PMID:23825022
competitive fitness: decreased
systematic mutation set

fitness profiling after 15 generations

null
Allele: sed1-Δ
S288CMedia: alkaline conditions, pH 8
Giaever G, et al. (2002) PMID:12140549
competitive fitness: decreased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: sed1-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 0.998
Breslow DK, et al. (2008) PMID:18622397
competitive fitness: decreased
systematic mutation setnull
Allele: sed1-Δ
S288C ethanolQian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: sed1-Δ
S288CMedia: glycerol medium, YPG
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: sed1-Δ
S288CMedia: synthetic oak exudate medium, OAK
Qian W, et al. (2012) PMID:23103169
competitive fitness: increased
systematic mutation setnull
Allele: sed1-Δ
S288CMedia: synthetic complete medium, SC
Qian W, et al. (2012) PMID:23103169
oxidative stress resistance: decreased
classical geneticsnull
Allele: sed1-Δ
SEY6210500 uM 1,1'-azobis(N,N-dimethylformamide)Ezaki B, et al. (1998) PMID:9485599
resistance to chemicals: decreased
heterozygous diploidnull
Allele: sed1-Δ
S288CIC50 23.2 uM nelfinavirShim JS, et al. (2012) PMID:23042933
resistance to chemicals: decreased
homozygous diploid, systematic mutation setnull
Allele: sed1-Δ
S288Ctunicamycin B tunicamycinHoepfner D, et al. (2014) PMID:24360837
Showing 1 to 10 of 25 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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