MSW1 / YDR268W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

MSW1/YDR68W is a non-essential gene; null mutants are viable but exhibit a range of phenotypic changes including increased mitochondrial rho- mutation frequency, increased replicative lifespan, absent respiratory growth, decreased acid pH resistance, decreased chronological lifespan, decreased competitive fitness, decreased filamentous growth, increased heat sensitivity, decreased hyperosmotic stress resistance, absent invasive growth, abnormal lipid particle morphology, absent or decreased mitochondrial genome maintenance, increased oxidative stress resistance, decreased UV resistance, abnormal vacuolar morphology, decreased vegetative growth rate, absent or decreased utilization of carbon sources, and decreased respiratory growth rate. Reduction of function mutants exhibit absent or decreased respiratory growth rate. Overexpression of MSW1 results in decreased filamentous growth and absent invasive growth.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources