GPI8 / YDR331W Homology


Standard Name
GPI8 1
Systematic Name
YDR331W
SGD ID
SGD:S000002739
Feature Type
ORF , Verified
Description
Catalytic subunit of the ER membrane GPI transamidase complex; involved in adding glycosylphosphatidylinositol (GPI) anchors to newly synthesized proteins; luminally-oriented type I integral membrane glycoprotein of the ER; human PIGK protein is a functional homolog 2 3 4
Name Description
GlycosylPhosphatidylInositol anchor biosynthesis 1
Comparative Info

Homologs

Homology calls are sourced from the Alliance of Genome Resources. Many aspects of data integration presented at the Alliance require a common set of orthology relationships among genes for the organisms represented, including human. The Alliance provides the results of all methods that have been benchmarked by the Quest for Orthologs Consortium (QfO). The homolog inferences from the different methods have been integrated using the DRSC Integrative Ortholog Prediction Tool (DIOPT), which integrates a number of existing methods including those used by the Alliance: Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, and ZFIN.

7 entries for 7 homologs


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SpeciesGene IDGene nameSource
Caenorhabditis elegansWB:WBGene00011482pigk-1Alliance
Danio rerioZFIN:ZDB-GENE-040625-162pigkAlliance
Drosophila melanogasterFB:FBgn0023545PIG-KAlliance
Homo sapiensHGNC:8965PIGKAlliance
Mus musculusMGI:1913863PigkAlliance
Rattus norvegicusRGD:1306753PigkAlliance
Xenopus tropicalisXenbase:XB-GENE-962876pigkAlliance
Showing 1 to 7 of 7 entries

Functional Complementation

Information about cross-species functional complementation between yeast and other species, curated by SGD and the Princeton Protein Orthology Database (P-POD).

2 entries for 2 complements


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SpeciesGene IDStrain backgroundDirectionDetailsSourceReference
Homo sapiensHGNC:8965S288Cother complements yeastHuman PIGK rescues the temperature sensitive growth defect of an S. cerevisiae gpi7-1 gpi8-1 double mutant.SGDBenghezal M, et al. (1996)
PMID:8978684
Homo sapiensHGNC:8965S288Cother complements yeastP-PODDe Sampaïo G, et al. (1999)
PMID:10564469
Showing 1 to 2 of 2 entries

Fungal Homologs

Fungal Homology calls are sourced from AllianceMine, which compiles fungal homology calls from FungiDB, CGD, Panther, PomBase, TreeFam, HomoloGene, and SGD.

17 entries for 17 homologs


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SpeciesGene IDGene nameDescriptionSource
A. flavus NRRL3357AFLA_084270FungiDB
A. niger ATCC 1015ASPNIDRAFT_205426FungiDB
C. gattii WM276CGB_F1560CFungiDB
C. immitis H538.4CIHG_00372FungiDB
C. immitis RSCIMG_03321FungiDB
C. neoformans var. grubii H99CNAG_06655FungiDB
C. neoformans var. neoformans JEC21CNF03660FungiDB
C. posadasii C735 delta SOWgpCPC735_008810FungiDB
N. crassa OR74ANCU11795FungiDB
S. pombeSPCC11E10.02cPomBase
Showing 1 to 10 of 17 entries

External Identifiers

List of external identifiers for the protein from various database sources.

20 entries for 10 sources


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External IDSource
AN0871AspGD
orf19.2799CGD
5371DIP
AAS56120.1GenBank/EMBL/DDBJ
AAB64766.1GenBank/EMBL/DDBJ
AY557794GenBank/EMBL/DDBJ
6320538GenBank/EMBL/DDBJ
45269479GenBank/EMBL/DDBJ
1351809GenBank/EMBL/DDBJ
914991GenBank/EMBL/DDBJ
Showing 1 to 10 of 20 entries

Resources