EFT2 / YDR385W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

EFT2/YDR385W is a non-essential gene; null mutants are viable but exhibit decreased competitive fitness, decreased anaerobic growth, auxotrophy, increased heat sensitivity, increased oxidative stress resistance, increased replicative lifespan, increased rate of respiratory growth, increased stress resistance, abnormal vacuolar morphology, and decreased rate of vegetative growth. Reduction of function mutants show increased acid pH resistance and increased vegetative growth. Conditional mutants display increased heat sensitivity and decreased vegetative growth. Overexpression of EFT2 results in decreased vegetative growth and a decreased rate of vegetative growth.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources