PGD1 / YGL025C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

PGD1/YGL025C is non-essential; null mutants are viable and exhibit decreased budding index, competitive fitness, desiccation resistance, innate thermotolerance, mitotic recombination, pheromone production, replicative lifespan, silencing, sporulation, starvation resistance, telomere length, toxin resistance, transposable element transposition, and vegetative growth rate. They also show abnormal chromosome/plasmid maintenance, increased heat sensitivity, decreased resistance to hyperosmotic, osmotic, and oxidative stress, and decreased utilization of carbon and sulfur sources. Overexpression of PGD1/YGL025C results in decreased metal and UV resistance.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources