PNC1 / YGL037C Homology


Standard Name
PNC1 1
Systematic Name
YGL037C
SGD ID
SGD:S000003005
Feature Type
ORF , Verified
Description
Nicotinamidase that converts nicotinamide to nicotinic acid; part of the NAD(+) salvage pathway; required for life span extension by calorie restriction; lacks a peroxisomal targeting signal but is imported into peroxisomes via binding to Gpd1p; PNC1 expression responds to all known stimuli that extend replicative life span; protein increases in abundance and relative distribution to cytoplasmic foci decreases upon DNA replication stress 1 2 3 4
Name Description
Pyrazinamidase and NiCotinamidase 1
Comparative Info

Homologs

Homology calls are sourced from the Alliance of Genome Resources. Many aspects of data integration presented at the Alliance require a common set of orthology relationships among genes for the organisms represented, including human. The Alliance provides the results of all methods that have been benchmarked by the Quest for Orthologs Consortium (QfO). The homolog inferences from the different methods have been integrated using the DRSC Integrative Ortholog Prediction Tool (DIOPT), which integrates a number of existing methods including those used by the Alliance: Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, and ZFIN.

3 entries for 3 homologs


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SpeciesGene IDGene nameSource
Caenorhabditis elegansWB:WBGene00021395pnc-1Alliance
Caenorhabditis elegansWB:WBGene00013336pnc-2Alliance
Drosophila melanogasterFB:FBgn0051216NaamAlliance
Showing 1 to 3 of 3 entries

Functional Complementation

Information about cross-species functional complementation between yeast and other species, curated by SGD and the Princeton Protein Orthology Database (P-POD).

0 entries for 0 complements


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SpeciesGene IDStrain backgroundDirectionDetailsSourceReference
No complement data for PNC1
Showing 0 to 0 of 0 entries

Fungal Homologs

Fungal Homology calls are sourced from AllianceMine, which compiles fungal homology calls from FungiDB, CGD, Panther, PomBase, TreeFam, HomoloGene, and SGD.


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Species Gene ID Gene name Description Source

External Identifiers

List of external identifiers for the protein from various database sources.

51 entries for 12 sources


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External IDSource
AN3809AspGD
orf19.6684CGD
2070DIP
3.5.1.19ExPASy
Z72559GenBank/EMBL/DDBJ
AAS56807.1GenBank/EMBL/DDBJ
CAA96739.1GenBank/EMBL/DDBJ
AY558481GenBank/EMBL/DDBJ
1322518GenBank/EMBL/DDBJ
374074558GenBank/EMBL/DDBJ
Showing 1 to 10 of 51 entries

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