Literature Help
SRM1 / YGL097W Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
- Unique References
- 166
- Aliases
-
MTR1
6
,
PRP20
7
,
TSM437
8
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Aguilar LC, et al. (2020) Altered rRNA processing disrupts nuclear RNA homeostasis via competition for the poly(A)-binding protein Nab2. Nucleic Acids Res 48(20):11675-11694 PMID:33137177
- Herrero E, et al. (2020) Asymmetric Transcription Factor Partitioning During Yeast Cell Division Requires the FACT Chromatin Remodeler and Cell Cycle Progression. Genetics 216(3):701-716 PMID:32878900
- Paul B and Montpetit B (2016) Altered RNA processing and export lead to retention of mRNAs near transcription sites and nuclear pore complexes or within the nucleolus. Mol Biol Cell 27(17):2742-56 PMID:27385342
- Wu J, et al. (2015) Genome-wide screen uncovers novel pathways for tRNA processing and nuclear-cytoplasmic dynamics. Genes Dev 29(24):2633-44 PMID:26680305
- Okada N, et al. (2014) Comprehensive analysis of genes involved in the oxidative stress tolerance using yeast heterozygous deletion collection. FEMS Yeast Res 14(3):425-34 PMID:24410772
- Makanae K, et al. (2013) Identification of dosage-sensitive genes in Saccharomyces cerevisiae using the genetic tug-of-war method. Genome Res 23(2):300-11 PMID:23275495
- Wu F, et al. (2011) The 1.9Å crystal structure of Prp20p from Saccharomyces cerevisiae and its binding properties to Gsp1p and histones. J Struct Biol 174(1):213-22 PMID:21093592
- Scott RJ, et al. (2009) The nuclear export factor Xpo1p targets Mad1p to kinetochores in yeast. J Cell Biol 184(1):21-9 PMID:19139260
- Hahn S, et al. (2008) Classical NLS proteins from Saccharomyces cerevisiae. J Mol Biol 379(4):678-94 PMID:18485366
- Clément M, et al. (2006) The nuclear GTPase Gsp1p can affect proper telomeric function through the Sir4 protein in Saccharomyces cerevisiae. Mol Microbiol 62(2):453-68 PMID:16956377
- Dilworth DJ, et al. (2005) The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in endogenous NPC-mediated transcriptional control. J Cell Biol 171(6):955-65 PMID:16365162
- Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 PMID:14574415
- Fichtner L and Schaffrath R (2002) KTI11 and KTI13, Saccharomyces cerevisiae genes controlling sensitivity to G1 arrest induced by Kluyveromyces lactis zymocin. Mol Microbiol 44(3):865-75 PMID:11994165
- Akhtar N, et al. (2001) Functional analysis of the yeast Ran exchange factor Prp20p: in vivo evidence for the RanGTP gradient model. Mol Genet Genomics 265(5):851-64 PMID:11523802
- Baker RP, et al. (2001) Interaction between Ran and Mog1 is required for efficient nuclear protein import. J Biol Chem 276(44):41255-62 PMID:11509570
- Clément M, et al. (2001) Overexpression of Bud5p can suppress mutations in the Gsp1p guanine nucleotide exchange factor Prp20p in Saccharomyces cerevisiae. Mol Genet Genomics 266(1):20-7 PMID:11589573
- Denning D, et al. (2001) The nucleoporin Nup60p functions as a Gsp1p-GTP-sensitive tether for Nup2p at the nuclear pore complex. J Cell Biol 154(5):937-50 PMID:11535617
- Gleizes PE, et al. (2001) Ultrastructural localization of rRNA shows defective nuclear export of preribosomes in mutants of the Nup82p complex. J Cell Biol 155(6):923-36 PMID:11739405
- Grosshans H, et al. (2001) Biogenesis of the signal recognition particle (SRP) involves import of SRP proteins into the nucleolus, assembly with the SRP-RNA, and Xpo1p-mediated export. J Cell Biol 153(4):745-62 PMID:11352936
- Stage-Zimmermann T, et al. (2000) Factors affecting nuclear export of the 60S ribosomal subunit in vivo. Mol Biol Cell 11(11):3777-89 PMID:11071906
- Nakashima N, et al. (1999) Saccharomyces cerevisiae putative G protein, Gtr1p, which forms complexes with itself and a novel protein designated as Gtr2p, negatively regulates the Ran/Gsp1p G protein cycle through Gtr2p. Genetics 152(3):853-67 PMID:10388807
- Seedorf M, et al. (1999) Interactions between a nuclear transporter and a subset of nuclear pore complex proteins depend on Ran GTPase. Mol Cell Biol 19(2):1547-57 PMID:9891088
- Taura T, et al. (1997) Yrb2p is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologue. J Biol Chem 272(50):31877-84 PMID:9395535
- Fleischmann M, et al. (1996) Allele-specific suppression of a Saccharomyces cerevisiae prp20 mutation by overexpression of a nuclear serine/threonine protein kinase. Mol Gen Genet 250(5):614-25 PMID:8676864
- Hayashi N, et al. (1996) Genetic interaction of DED1 encoding a putative ATP-dependent RNA helicase with SRM1 encoding a mammalian RCC1 homolog in Saccharomyces cerevisiae. Mol Gen Genet 253(1-2):149-56 PMID:9003298
- Koepp DM, et al. (1996) Dynamic localization of the nuclear import receptor and its interactions with transport factors. J Cell Biol 133(6):1163-76 PMID:8682856
- Kadowaki T, et al. (1994) Isolation and characterization of Saccharomyces cerevisiae mRNA transport-defective (mtr) mutants. J Cell Biol 126(3):649-59 PMID:8045930
- Kirkpatrick D and Solomon F (1994) Overexpression of yeast homologs of the mammalian checkpoint gene RCC1 suppresses the class of alpha-tubulin mutations that arrest with excess microtubules. Genetics 137(2):381-92 PMID:8070652
- Lee A, et al. (1994) Site-directed mutagenesis of the yeast PRP20/SRM1 gene reveals distinct activity domains in the protein product. Mol Gen Genet 245(1):32-44 PMID:7845357
- Amberg DC, et al. (1993) Nuclear PRP20 protein is required for mRNA export. EMBO J 12(1):233-41 PMID:7679070
- Belhumeur P, et al. (1993) GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization. Mol Cell Biol 13(4):2152-61 PMID:8455603
- Lee A, et al. (1993) Prp20, the Saccharomyces cerevisiae homolog of the regulator of chromosome condensation, RCC1, interacts with double-stranded DNA through a multi-component complex containing GTP-binding proteins. J Cell Sci 106 ( Pt 1):287-98 PMID:8270631
- Clark KL, et al. (1991) The yeast SRM1 protein and human RCC1 protein share analogous functions. Cell Regul 2(10):781-92 PMID:1666302
- Fleischmann M, et al. (1991) Analysis of yeast prp20 mutations and functional complementation by the human homologue RCC1, a protein involved in the control of chromosome condensation. Mol Gen Genet 227(3):417-23 PMID:1865879
- Ohtsubo M, et al. (1991) Mutation of the hamster cell cycle gene RCC1 is complemented by the homologous genes of Drosophila and S.cerevisiae. EMBO J 10(5):1265-73 PMID:2022190
- Aebi M, et al. (1990) A yeast mutant, PRP20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation. Mol Gen Genet 224(1):72-80 PMID:2277633
- Clark KL and Sprague GF (1989) Yeast pheromone response pathway: characterization of a suppressor that restores mating to receptorless mutants. Mol Cell Biol 9(6):2682-94 PMID:2548085
- Vijayraghavan U, et al. (1989) Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae. Genes Dev 3(8):1206-16 PMID:2676722
- Fried HM and Warner JR (1982) Molecular cloning and analysis of yeast gene for cycloheximide resistance and ribosomal protein L29. Nucleic Acids Res 10(10):3133-48 PMID:6285288
Related Literature
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Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Stochaj U (2024) Yeast profilin mutants inhibit classical nuclear import and alter the balance between actin and tubulin levels. Biochem Cell Biol 102(2):206-212 PMID:38048555
- Hwang WY, et al. (2022) Kap-β2/Transportin mediates β-catenin nuclear transport in Wnt signaling. Elife 11 PMID:36300792
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Van Dalfsen KM, et al. (2018) Global Proteome Remodeling during ER Stress Involves Hac1-Driven Expression of Long Undecoded Transcript Isoforms. Dev Cell 46(2):219-235.e8 PMID:30016623
- Jennings MJ, et al. (2016) Elimination of truncated recombinant protein expressed in Escherichia coli by removing cryptic translation initiation site. Protein Expr Purif 121:17-21 PMID:26739786
- Jovičić A, et al. (2015) Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS. Nat Neurosci 18(9):1226-9 PMID:26308983
- Petelinc T, et al. (2013) Insight into the molecular mechanisms of propolis activity using a subcellular proteomic approach. J Agric Food Chem 61(47):11502-10 PMID:24195611
- Roman N, et al. (2013) Structural characterisation of the nuclear import receptor importin alpha in complex with the bipartite NLS of Prp20. PLoS One 8(12):e82038 PMID:24339986
- Ma Z, et al. (2012) Multiple roles for the Ess1 prolyl isomerase in the RNA polymerase II transcription cycle. Mol Cell Biol 32(17):3594-607 PMID:22778132
- Stirling PC, et al. (2012) R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants. Genes Dev 26(2):163-75 PMID:22279048
- Hahn S and Schlenstedt G (2011) Importin β-type nuclear transport receptors have distinct binding affinities for Ran-GTP. Biochem Biophys Res Commun 406(3):383-8 PMID:21329658
- Serpeloni M, et al. (2011) Comparative genomics of proteins involved in RNA nucleocytoplasmic export. BMC Evol Biol 11:7 PMID:21223572
- Smith SB, et al. (2011) Pronounced and extensive microtubule defects in a Saccharomyces cerevisiae DIS3 mutant. Yeast 28(11):755-69 PMID:21919057
- Dawson TR, et al. (2009) ER membrane-bending proteins are necessary for de novo nuclear pore formation. J Cell Biol 184(5):659-75 PMID:19273614
- Koerber RT, et al. (2009) Interaction of transcriptional regulators with specific nucleosomes across the Saccharomyces genome. Mol Cell 35(6):889-902 PMID:19782036
- Nguyen Ba AN, et al. (2009) NLStradamus: a simple Hidden Markov Model for nuclear localization signal prediction. BMC Bioinformatics 10:202 PMID:19563654
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Casanova M, et al. (2008) Inhibition of active nuclear transport is an intrinsic trigger of programmed cell death in trypanosomatids. Cell Death Differ 15(12):1910-20 PMID:19011643
- Del Vescovo V, et al. (2008) Role of Hog1 and Yaf9 in the transcriptional response of Saccharomyces cerevisiae to cesium chloride. Physiol Genomics 33(1):110-20 PMID:18198280
- Patel SS and Rexach MF (2008) Discovering novel interactions at the nuclear pore complex using bead halo: a rapid method for detecting molecular interactions of high and low affinity at equilibrium. Mol Cell Proteomics 7(1):121-31 PMID:17897934
- Caesar S, et al. (2006) Kap120 functions as a nuclear import receptor for ribosome assembly factor Rpf1 in yeast. Mol Cell Biol 26(8):3170-80 PMID:16581791
- De Hertogh B, et al. (2006) Emergence of species-specific transporters during evolution of the hemiascomycete phylum. Genetics 172(2):771-81 PMID:16118182
- Goffin L, et al. (2006) The unfolded protein response transducer Ire1p contains a nuclear localization sequence recognized by multiple beta importins. Mol Biol Cell 17(12):5309-23 PMID:17035634
- Burckin T, et al. (2005) Exploring functional relationships between components of the gene expression machinery. Nat Struct Mol Biol 12(2):175-82 PMID:15702072
- Makrantoni V, et al. (2005) Rapid enrichment and analysis of yeast phosphoproteins using affinity chromatography, 2D-PAGE and peptide mass fingerprinting. Yeast 22(5):401-14 PMID:15806615
- Saitoh YH, et al. (2005) Brl1p -- a novel nuclear envelope protein required for nuclear transport. Traffic 6(6):502-17 PMID:15882446
- Tanaka K, et al. (2005) Molecular mechanisms of kinetochore capture by spindle microtubules. Nature 434(7036):987-94 PMID:15846338
- Wang Y, et al. (2005) Saccharomyces cerevisiae GTPase complex: Gtr1p-Gtr2p regulates cell-proliferation through Saccharomyces cerevisiae Ran-binding protein, Yrb2p. Biochem Biophys Res Commun 336(2):639-45 PMID:16143306
- Loch CM, et al. (2004) Functional and physical interactions between autonomously replicating sequence-binding factor 1 and the nuclear transport machinery. Traffic 5(12):925-35 PMID:15522095
- Quan X, et al. (2004) Regulated nuclear accumulation of the yeast hsp70 Ssa4p in ethanol-stressed cells is mediated by the N-terminal domain, requires the nuclear carrier Nmd5p and protein kinase C. FASEB J 18(7):899-901 PMID:15001563
- Gao H, et al. (2003) Nuclear accumulation of the small GTPase Gsp1p depends on nucleoporins Nup133p, Rat2p/Nup120p, Nup85p, Nic96p, and the acetyl-CoA carboxylase Acc1p. J Biol Chem 278(28):25331-40 PMID:12730220
- Ryan KJ, et al. (2003) The Ran GTPase cycle is required for yeast nuclear pore complex assembly. J Cell Biol 160(7):1041-53 PMID:12654904
- Fischer N and Weis K (2002) The DEAD box protein Dhh1 stimulates the decapping enzyme Dcp1. EMBO J 21(11):2788-97 PMID:12032091
- Stade K, et al. (2002) A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast. J Biol Chem 277(51):49554-61 PMID:12393908
- Zhang J, et al. (2002) Genomic scale mutant hunt identifies cell size homeostasis genes in S. cerevisiae. Curr Biol 12(23):1992-2001 PMID:12477387
- Brodsky AS and Silver PA (2000) Pre-mRNA processing factors are required for nuclear export. RNA 6(12):1737-49 PMID:11142374
- Stochaj U, et al. (2000) Stress-mediated inhibition of the classical nuclear protein import pathway and nuclear accumulation of the small GTPase Gsp1p. FASEB J 14(14):2130-2 PMID:11024003
- Vainberg IE, et al. (2000) Nuclear export of heat shock and non-heat-shock mRNA occurs via similar pathways. Mol Cell Biol 20(11):3996-4005 PMID:10805742
- Booth JW, et al. (1999) The yeast nucleoporin Nup2p is involved in nuclear export of importin alpha/Srp1p. J Biol Chem 274(45):32360-7 PMID:10542277
- Feng W, et al. (1999) Antagonistic effects of NES and NLS motifs determine S. cerevisiae Rna1p subcellular distribution. J Cell Sci 112 ( Pt 3):339-47 PMID:9885287
- Hurt E, et al. (1999) A novel in vivo assay reveals inhibition of ribosomal nuclear export in ran-cycle and nucleoporin mutants. J Cell Biol 144(3):389-401 PMID:9971735
- Matynia A, et al. (1998) Isolation and characterization of fission yeast sns mutants defective at the mitosis-to-interphase transition. Genetics 148(4):1799-811 PMID:9560394
- Yan C, et al. (1998) Crm1p mediates regulated nuclear export of a yeast AP-1-like transcription factor. EMBO J 17(24):7416-29 PMID:9857197
- Azuma Y, et al. (1997) Inhibition by anti-RCC1 monoclonal antibodies of RCC1-stimulated guanine nucleotide exchange on Ran GTPase. J Biochem 122(6):1133-8 PMID:9498556
- Floer M, et al. (1997) Disassembly of RanGTP-karyopherin beta complex, an intermediate in nuclear protein import. J Biol Chem 272(31):19538-46 PMID:9235958
- Noguchi E, et al. (1997) Yrb2p, a Nup2p-related yeast protein, has a functional overlap with Rna1p, a yeast Ran-GTPase-activating protein. Mol Cell Biol 17(4):2235-46 PMID:9121474
- Nakashima N, et al. (1996) Putative GTPase Gtr1p genetically interacts with the RanGTPase cycle in Saccharomyces cerevisiae. J Cell Sci 109 ( Pt 9):2311-8 PMID:8886981
- Noguchi E, et al. (1996) Dis3, implicated in mitotic control, binds directly to Ran and enhances the GEF activity of RCC1. EMBO J 15(20):5595-605 PMID:8896453
- Saavedra C, et al. (1996) Regulation of mRNA export in response to stress in Saccharomyces cerevisiae. Genes Dev 10(13):1608-20 PMID:8682292
- Hayashi N, et al. (1995) RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4. Mol Gen Genet 247(6):661-9 PMID:7616957
- Butler G and Wolfe KH (1994) Yeast homologue of mammalian Ran binding protein 1. Biochim Biophys Acta 1219(3):711-2 PMID:7948031
- Merkle T, et al. (1994) Phenotype of the fission yeast cell cycle regulatory mutant pim1-46 is suppressed by a tobacco cDNA encoding a small, Ran-like GTP-binding protein. Plant J 6(4):555-65 PMID:7987414
- Kadowaki T, et al. (1993) Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily. EMBO J 12(7):2929-37 PMID:7687541
- Forrester W, et al. (1992) Defects in mRNA 3'-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: possible coupling of mRNA processing and chromatin structure. Genes Dev 6(10):1914-26 PMID:1398069
- Kadowaki T, et al. (1992) A conditional yeast mutant deficient in mRNA transport from nucleus to cytoplasm. Proc Natl Acad Sci U S A 89(6):2312-6 PMID:1372441
- Su JY, et al. (1990) Genetic and molecular analysis of the SOE1 gene: a tRNA(3Glu) missense suppressor of yeast cdc8 mutations. Genetics 124(3):523-31 PMID:2155851
- Mortimer RK and Hawthorne DC (1973) Genetic Mapping in Saccharomyces IV. Mapping of Temperature-Sensitive Genes and Use of Disomic Strains in Localizing Genes. Genetics 74(1):33-54 PMID:17248609
Reviews
No reviews curated.
Download References (.nbib)
- Gräf R (2018) Comparative Biology of Centrosomal Structures in Eukaryotes. Cells 7(11) PMID:30413081
- Yedidi RS, et al. (2016) Proteasome dynamics between proliferation and quiescence stages of Saccharomyces cerevisiae. Crit Rev Biochem Mol Biol 51(6):497-512 PMID:27677933
- Burns LT and Wente SR (2014) From hypothesis to mechanism: uncovering nuclear pore complex links to gene expression. Mol Cell Biol 34(12):2114-20 PMID:24615017
- Frankel MB and Knoll LJ (2009) The ins and outs of nuclear trafficking: unusual aspects in apicomplexan parasites. DNA Cell Biol 28(6):277-84 PMID:19348590
- Henras AK, et al. (2008) The post-transcriptional steps of eukaryotic ribosome biogenesis. Cell Mol Life Sci 65(15):2334-59 PMID:18408888
- Zemp I and Kutay U (2007) Nuclear export and cytoplasmic maturation of ribosomal subunits. FEBS Lett 581(15):2783-93 PMID:17509569
- Künzler M and Hurt E (2001) Targeting of Ran: variation on a common theme? J Cell Sci 114(Pt 18):3233-41 PMID:11591812
- Cole CN and Hammell CM (1998) Nucleocytoplasmic transport: driving and directing transport. Curr Biol 8(11):R368-72 PMID:9635180
- Fabre E and Hurt E (1997) Yeast genetics to dissect the nuclear pore complex and nucleocytoplasmic trafficking. Annu Rev Genet 31:277-313 PMID:9442897
- Wente SR, et al. (1997) "The nucleus and nucleocytoplasmic transport in Saccharomyces cerevisiae." Pp. 471-546 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Cell Cycle and Cell Biology, edited by Pringle JR, Broach JR and Jones EW. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Download References (.nbib)
- Paul B and Montpetit B (2016) Altered RNA processing and export lead to retention of mRNAs near transcription sites and nuclear pore complexes or within the nucleolus. Mol Biol Cell 27(17):2742-56 PMID:27385342
- Dilworth DJ, et al. (2005) The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in endogenous NPC-mediated transcriptional control. J Cell Biol 171(6):955-65 PMID:16365162
- Gleizes PE, et al. (2001) Ultrastructural localization of rRNA shows defective nuclear export of preribosomes in mutants of the Nup82p complex. J Cell Biol 155(6):923-36 PMID:11739405
- Stochaj U, et al. (2000) Stress-mediated inhibition of the classical nuclear protein import pathway and nuclear accumulation of the small GTPase Gsp1p. FASEB J 14(14):2130-2 PMID:11024003
- Belhumeur P, et al. (1993) GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization. Mol Cell Biol 13(4):2152-61 PMID:8455603
- Clark KL, et al. (1991) The yeast SRM1 protein and human RCC1 protein share analogous functions. Cell Regul 2(10):781-92 PMID:1666302
- Fleischmann M, et al. (1991) Analysis of yeast prp20 mutations and functional complementation by the human homologue RCC1, a protein involved in the control of chromosome condensation. Mol Gen Genet 227(3):417-23 PMID:1865879
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Download References (.nbib)
- Hayashi N and Oki M (2020) Altered metabolic regulation owing to gsp1 mutations encoding the nuclear small G protein in Saccharomyces cerevisiae. Curr Genet 66(2):335-344 PMID:31372715
- Herrero E, et al. (2020) Asymmetric Transcription Factor Partitioning During Yeast Cell Division Requires the FACT Chromatin Remodeler and Cell Cycle Progression. Genetics 216(3):701-716 PMID:32878900
- Makanae K, et al. (2013) Identification of dosage-sensitive genes in Saccharomyces cerevisiae using the genetic tug-of-war method. Genome Res 23(2):300-11 PMID:23275495
- Kupke T, et al. (2011) Targeting of Nbp1 to the inner nuclear membrane is essential for spindle pole body duplication. EMBO J 30(16):3337-52 PMID:21785410
- Clément M, et al. (2006) The nuclear GTPase Gsp1p can affect proper telomeric function through the Sir4 protein in Saccharomyces cerevisiae. Mol Microbiol 62(2):453-68 PMID:16956377
- Grosshans H, et al. (2001) Biogenesis of the signal recognition particle (SRP) involves import of SRP proteins into the nucleolus, assembly with the SRP-RNA, and Xpo1p-mediated export. J Cell Biol 153(4):745-62 PMID:11352936
- Kadowaki T, et al. (1994) Isolation and characterization of Saccharomyces cerevisiae mRNA transport-defective (mtr) mutants. J Cell Biol 126(3):649-59 PMID:8045930
- Fleischmann M, et al. (1991) Analysis of yeast prp20 mutations and functional complementation by the human homologue RCC1, a protein involved in the control of chromosome condensation. Mol Gen Genet 227(3):417-23 PMID:1865879
- Vijayraghavan U, et al. (1989) Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae. Genes Dev 3(8):1206-16 PMID:2676722
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- Marmorale LJ, et al. (2024) Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking. J Cell Biol 223(3) PMID:38240799
- O'Brien MJ and Ansari A (2024) Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle. Biochim Biophys Acta Proteins Proteom 1872(1):140968 PMID:37863410
- Ali A, et al. (2023) Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates. Nat Cell Biol 25(11):1691-1703 PMID:37845327
- Kolhe JA, et al. (2023) The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions. Mol Cell 83(12):2035-2044.e7 PMID:37295430
- Litwin I, et al. (2023) ISW1a modulates cohesin distribution in centromeric and pericentromeric regions. Nucleic Acids Res 51(17):9101-9121 PMID:37486771
- Michaelis AC, et al. (2023) The social and structural architecture of the yeast protein interactome. Nature 624(7990):192-200 PMID:37968396
- Mishra PK, et al. (2023) Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability. Mol Biol Cell 34(10):ar99 PMID:37436802
- Barkova A, et al. (2022) A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition. Mob DNA 13(1):26 PMID:36401307
- Gopalakrishnan R and Winston F (2021) The histone chaperone Spt6 is required for normal recruitment of the capping enzyme Abd1 to transcribed regions. J Biol Chem 297(4):101205 PMID:34543624
- Perica T, et al. (2021) Systems-level effects of allosteric perturbations to a model molecular switch. Nature 599(7883):152-157 PMID:34646016
- Au WC, et al. (2020) Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast. PLoS Genet 16(2):e1008597 PMID:32032354
- Sanders E, et al. (2020) Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1. G3 (Bethesda) 10(12):4359-4368 PMID:33115720
- Bhalla P, et al. (2019) Interactome of the yeast RNA polymerase III transcription machinery constitutes several chromatin modifiers and regulators of the genes transcribed by RNA polymerase II. Gene 702:205-214 PMID:30593915
- Pereira F, et al. (2019) Effect of Sec61 interaction with Mpd1 on endoplasmic reticulum-associated degradation. PLoS One 14(1):e0211180 PMID:30682149
- Wild P, et al. (2019) Network Rewiring of Homologous Recombination Enzymes during Mitotic Proliferation and Meiosis. Mol Cell 75(4):859-874.e4 PMID:31351878
- Gay S, et al. (2018) A Mad2-Mediated Translational Regulatory Mechanism Promoting S-Phase Cyclin Synthesis Controls Origin Firing and Survival to Replication Stress. Mol Cell 70(4):628-638.e5 PMID:29775579
- MacGilvray ME, et al. (2018) Network inference reveals novel connections in pathways regulating growth and defense in the yeast salt response. PLoS Comput Biol 13(5):e1006088 PMID:29738528
- Miller JE, et al. (2018) Genome-Wide Mapping of Decay Factor-mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4. G3 (Bethesda) 8(1):315-330 PMID:29158339
- Chymkowitch P, et al. (2017) TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity. Proc Natl Acad Sci U S A 114(5):1039-1044 PMID:28096404
- Izawa T, et al. (2017) Cytosolic Protein Vms1 Links Ribosome Quality Control to Mitochondrial and Cellular Homeostasis. Cell 171(4):890-903.e18 PMID:29107329
- Lapointe CP, et al. (2017) Architecture and dynamics of overlapped RNA regulatory networks. RNA 23(11):1636-1647 PMID:28768715
- Zander G, et al. (2017) Saccharomyces cerevisiae Gle2/Rae1 is involved in septin organization, essential for cell cycle progression. Yeast 34(11):459-470 PMID:28776765
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Jain S, et al. (2016) ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell 164(3):487-98 PMID:26777405
- Styles EB, et al. (2016) Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci. Cell Syst 3(3):264-277.e10 PMID:27617677
- Kurat CF, et al. (2014) Cell cycle-regulated oscillator coordinates core histone gene transcription through histone acetylation. Proc Natl Acad Sci U S A 111(39):14124-9 PMID:25228766
- van Pel DM, et al. (2013) Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork. G3 (Bethesda) 3(2):273-82 PMID:23390603
- Willmund F, et al. (2013) The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell 152(1-2):196-209 PMID:23332755
- Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801 PMID:22282571
- Wu F, et al. (2011) The 1.9Å crystal structure of Prp20p from Saccharomyces cerevisiae and its binding properties to Gsp1p and histones. J Struct Biol 174(1):213-22 PMID:21093592
- Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31 PMID:20093466
- Müller P, et al. (2010) The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin. Genes Dev 24(13):1418-33 PMID:20595233
- Hahn S, et al. (2008) Classical NLS proteins from Saccharomyces cerevisiae. J Mol Biol 379(4):678-94 PMID:18485366
- Caesar S, et al. (2006) Kap120 functions as a nuclear import receptor for ribosome assembly factor Rpf1 in yeast. Mol Cell Biol 26(8):3170-80 PMID:16581791
- Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43 PMID:16554755
- Dilworth DJ, et al. (2005) The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in endogenous NPC-mediated transcriptional control. J Cell Biol 171(6):955-65 PMID:16365162
- Saitoh YH, et al. (2005) Brl1p -- a novel nuclear envelope protein required for nuclear transport. Traffic 6(6):502-17 PMID:15882446
- Wang Y, et al. (2005) Saccharomyces cerevisiae GTPase complex: Gtr1p-Gtr2p regulates cell-proliferation through Saccharomyces cerevisiae Ran-binding protein, Yrb2p. Biochem Biophys Res Commun 336(2):639-45 PMID:16143306
- Graumann J, et al. (2004) Applicability of tandem affinity purification MudPIT to pathway proteomics in yeast. Mol Cell Proteomics 3(3):226-37 PMID:14660704
- Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 PMID:14574415
- Ho Y, et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature 415(6868):180-3 PMID:11805837
- Akhtar N, et al. (2001) Functional analysis of the yeast Ran exchange factor Prp20p: in vivo evidence for the RanGTP gradient model. Mol Genet Genomics 265(5):851-64 PMID:11523802
- Baker RP, et al. (2001) Interaction between Ran and Mog1 is required for efficient nuclear protein import. J Biol Chem 276(44):41255-62 PMID:11509570
- Lau D, et al. (2000) Purification of protein A-tagged yeast ran reveals association with a novel karyopherin beta family member, Pdr6p. J Biol Chem 275(1):467-71 PMID:10617640
- Booth JW, et al. (1999) The yeast nucleoporin Nup2p is involved in nuclear export of importin alpha/Srp1p. J Biol Chem 274(45):32360-7 PMID:10542277
- Nakashima N, et al. (1999) Saccharomyces cerevisiae putative G protein, Gtr1p, which forms complexes with itself and a novel protein designated as Gtr2p, negatively regulates the Ran/Gsp1p G protein cycle through Gtr2p. Genetics 152(3):853-67 PMID:10388807
- Oki M and Nishimoto T (1998) A protein required for nuclear-protein import, Mog1p, directly interacts with GTP-Gsp1p, the Saccharomyces cerevisiae ran homologue. Proc Natl Acad Sci U S A 95(26):15388-93 PMID:9860978
- Ouspenski II (1998) A RanBP1 mutation which does not visibly affect nuclear import may reveal additional functions of the ran GTPase system. Exp Cell Res 244(1):171-83 PMID:9770360
- Taura T, et al. (1998) A member of the Ran-binding protein family, Yrb2p, is involved in nuclear protein export. Proc Natl Acad Sci U S A 95(13):7427-32 PMID:9636166
- Noguchi E, et al. (1997) Yrb2p, a Nup2p-related yeast protein, has a functional overlap with Rna1p, a yeast Ran-GTPase-activating protein. Mol Cell Biol 17(4):2235-46 PMID:9121474
- Taura T, et al. (1997) Yrb2p is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologue. J Biol Chem 272(50):31877-84 PMID:9395535
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Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
Download References (.nbib)
- Leutert M, et al. (2023) The regulatory landscape of the yeast phosphoproteome. Nat Struct Mol Biol 30(11):1761-1773 PMID:37845410
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Zhou X, et al. (2021) Cross-compartment signal propagation in the mitotic exit network. Elife 10 PMID:33481703
- Chen YC, et al. (2018) Glucose intake hampers PKA-regulated HSP90 chaperone activity. Elife 7 PMID:30516470
- Swaney DL, et al. (2013) Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nat Methods 10(7):676-82 PMID:23749301
- Soulard A, et al. (2010) The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates. Mol Biol Cell 21(19):3475-86 PMID:20702584
- Holt LJ, et al. (2009) Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution. Science 325(5948):1682-6 PMID:19779198
- Huber A, et al. (2009) Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis. Genes Dev 23(16):1929-43 PMID:19684113
- Albuquerque CP, et al. (2008) A multidimensional chromatography technology for in-depth phosphoproteome analysis. Mol Cell Proteomics 7(7):1389-96 PMID:18407956
Functional Complementation Annotations Literature
Paper(s) associated with one or more pieces of functional complementation annotations evidence in SGD.
No functional complementation annotations literature curated.
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Coey CT and Clark DJ (2022) A systematic genome-wide account of binding sites for the model transcription factor Gcn4. Genome Res 32(2):367-377 PMID:34916251
- Forster DT, et al. (2022) BIONIC: biological network integration using convolutions. Nat Methods 19(10):1250-1261 PMID:36192463
- Herrero E, et al. (2020) Asymmetric Transcription Factor Partitioning During Yeast Cell Division Requires the FACT Chromatin Remodeler and Cell Cycle Progression. Genetics 216(3):701-716 PMID:32878900
- Ang JS, et al. (2016) Dosage Mutator Genes in Saccharomyces cerevisiae: A Novel Mutator Mode-of-Action of the Mph1 DNA Helicase. Genetics 204(3):975-986 PMID:27585847
- Okada N, et al. (2014) Comprehensive analysis of genes involved in the oxidative stress tolerance using yeast heterozygous deletion collection. FEMS Yeast Res 14(3):425-34 PMID:24410772
- Huang Z, et al. (2013) A functional variomics tool for discovering drug-resistance genes and drug targets. Cell Rep 3(2):577-85 PMID:23416056
- Neumüller RA, et al. (2013) Conserved regulators of nucleolar size revealed by global phenotypic analyses. Sci Signal 6(289):ra70 PMID:23962978
- Carrillo E, et al. (2012) Characterizing the roles of Met31 and Met32 in coordinating Met4-activated transcription in the absence of Met30. Mol Biol Cell 23(10):1928-42 PMID:22438580
- Lickwar CR, et al. (2012) Genome-wide protein-DNA binding dynamics suggest a molecular clutch for transcription factor function. Nature 484(7393):251-5 PMID:22498630
- Pir P, et al. (2012) The genetic control of growth rate: a systems biology study in yeast. BMC Syst Biol 6:4 PMID:22244311
- Stirling PC, et al. (2011) The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components. PLoS Genet 7(4):e1002057 PMID:21552543
- Venters BJ, et al. (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92 PMID:21329885
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549
- Jorgensen P, et al. (2002) Systematic identification of pathways that couple cell growth and division in yeast. Science 297(5580):395-400 PMID:12089449
- Zhang J, et al. (2002) Genomic scale mutant hunt identifies cell size homeostasis genes in S. cerevisiae. Curr Biol 12(23):1992-2001 PMID:12477387