SKI6 / YGR195W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Essential gene; ts mutants display delayed exit from stationary phase and sensitivity to benomyl and hygromycin B; mutant cells are enlarged, with large drooping buds that have elongated necks; repression or conditional mutations cause lowered levels of mature 5.8S rRNA and higher levels of many different RNA processing intermediates; in large-scale studies, repression causes chromosomal instability; mutations confer sensitivity to Calcofluor White and resistance to cycloheximide; diploid heterozygous null mutant is haploinsufficient and sensitive to starvation

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources