Phenotype Help

PRY1 / YJL079C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

15 entries for 13 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
chemical compound accumulation: abnormal
systematic mutation setnull
Allele: pry1-Δ
S288C alpha-amino acidDetails: Significantly altered free amino acid profile (X^2- test p < 0.01)
Mülleder M, et al. (2016) PMID:27693354
chronological lifespan: decreased
systematic mutation setnull
Allele: pry1-Δ
S288CLaschober GT, et al. (2010) PMID:20883526
competitive fitness: decreased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: pry1-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 0.989
Breslow DK, et al. (2008) PMID:18622397
filamentous growth: decreased
systematic mutation setnull
Allele: pry1-Δ
Sigma1278bJin R, et al. (2008) PMID:17989363
haploinsufficient
heterozygous diploid, competitive growth

genome-wide fitness profiling

null
Allele: pry1-Δ
S288CMedia: turbidostat growth in FPM medium
Details: Relative growth score: -0.0037
Pir P, et al. (2012) PMID:22244311
invasive growth: absent
systematic mutation setnull
Allele: pry1-Δ
Sigma1278bJin R, et al. (2008) PMID:17989363
resistance to chemicals: decreased
classical geneticsnull
Allele: pry1-Δ
Other eugenolChoudhary V and Schneiter R (2012) PMID:23027975
resistance to chemicals: decreased
competitive growth

fitness profiling of the non-essential deletion collection after 18 generations

null
Allele: pry1-Δ
S288C20 ug/ml cordycepinDetails: sensitivity increased two-fold or greater
Holbein S, et al. (2009) PMID:19324962
resistance to chemicals: decreased
systematic mutation set null
Allele: pry1-Δ
S288C15 μM EVP4593Media: nonfermentable carbon source
Details: greatly reduced or no growth on glycerol/ethanol containing media
Hiestand L, et al. (2023) PMID:37179969
resistance to chemicals: increased
large-scale survey

variomic library screening of ~10,000 alleles for each gene

unspecifiedS288C100 ng/ml cycloheximideHuang Z, et al. (2013) PMID:23416056
Showing 1 to 10 of 15 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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