CDC6 / YJL194W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Essential gene; repressible mutant arrests in S phase with partially replicated DNA; conditional mutant arrests with large budded cells and nuclei situated at the mother-bud neck; conditional mutant displays chromosomal instability with an elevated rate of chromosome loss and gross chromosomal rearrangements at semi-permissive temperatures; conditional mutant displays an increased mutation frequency at permissive temperature; overexpression results in a decreased rate of vegetative growth

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources