Literature Help
ELO1 / YJL196C Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Randez-Gil F, et al. (2020) Myriocin-induced adaptive laboratory evolution of an industrial strain of Saccharomyces cerevisiae reveals its potential to remodel lipid composition and heat tolerance. Microb Biotechnol 13(4):1066-1081 PMID:32212314
- Caudy AA, et al. (2019) Functional genetic discovery of enzymes using full-scan mass spectrometry metabolomics 1. Biochem Cell Biol 97(1):73-84 PMID:30001498
- Vamvakas SS, et al. (2019) Specific serine residues of Msn2/4 are responsible for regulation of alcohol fermentation rates and ethanol resistance. Biotechnol Prog 35(2):e2759 PMID:30507007
- Wang Q, et al. (2018) A critical role for very long-chain fatty acid elongases in oleic acid-mediated Saccharomyces cerevisiae cytotoxicity. Microbiol Res 207:1-7 PMID:29458843
- Villasmil ML, et al. (2017) A link between very long chain fatty acid elongation and mating-specific yeast cell cycle arrest. Cell Cycle 16(22):2192-2203 PMID:28745545
- Vazquez HM, et al. (2016) Chemogenetic E-MAP in Saccharomyces cerevisiae for Identification of Membrane Transporters Operating Lipid Flip Flop. PLoS Genet 12(7):e1006160 PMID:27462707
- Wu X, et al. (2016) Deletion of JJJ1 improves acetic acid tolerance and bioethanol fermentation performance of Saccharomyces cerevisiae strains. Biotechnol Lett 38(7):1097-106 PMID:27067354
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Sec P, et al. (2015) Baker's Yeast Deficient in Storage Lipid Synthesis Uses cis-Vaccenic Acid to Reduce Unsaturated Fatty Acid Toxicity. Lipids 50(7):621-30 PMID:25908426
- Aung HW, et al. (2013) Revising the Representation of Fatty Acid, Glycerolipid, and Glycerophospholipid Metabolism in the Consensus Model of Yeast Metabolism. Ind Biotechnol (New Rochelle N Y) 9(4):215-228 PMID:24678285
- Novo M, et al. (2013) Genome-wide study of the adaptation of Saccharomyces cerevisiae to the early stages of wine fermentation. PLoS One 8(9):e74086 PMID:24040173
- Lee YJ, et al. (2011) Defects in very long chain fatty acid synthesis enhance alpha-synuclein toxicity in a yeast model of Parkinson's disease. PLoS One 6(1):e15946 PMID:21264320
- Hodge CA, et al. (2010) Integral membrane proteins Brr6 and Apq12 link assembly of the nuclear pore complex to lipid homeostasis in the endoplasmic reticulum. J Cell Sci 123(Pt 1):141-51 PMID:20016074
- Lewis JA, et al. (2010) Exploiting natural variation in Saccharomyces cerevisiae to identify genes for increased ethanol resistance. Genetics 186(4):1197-205 PMID:20855568
- Rajakumari S, et al. (2010) Triacylglycerol lipolysis is linked to sphingolipid and phospholipid metabolism of the yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1801(12):1314-22 PMID:20727985
- Chertemps T, et al. (2005) A new elongase selectively expressed in Drosophila male reproductive system. Biochem Biophys Res Commun 333(4):1066-72 PMID:15975553
- Rössler H, et al. (2003) Functional differentiation and selective inactivation of multiple Saccharomyces cerevisiae genes involved in very-long-chain fatty acid synthesis. Mol Genet Genomics 269(2):290-8 PMID:12684876
- Schneiter R, et al. (2000) Elo1p-dependent carboxy-terminal elongation of C14:1Delta(9) to C16:1Delta(11) fatty acids in Saccharomyces cerevisiae. J Bacteriol 182(13):3655-60 PMID:10850979
- Tvrdik P, et al. (2000) Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids. J Cell Biol 149(3):707-18 PMID:10791983
- Zank TK, et al. (2000) Cloning and functional expression of the first plant fatty acid elongase specific for Delta(6)-polyunsaturated fatty acids. Biochem Soc Trans 28(6):654-8 PMID:11171159
- Dittrich F, et al. (1998) Fatty acid elongation in yeast--biochemical characteristics of the enzyme system and isolation of elongation-defective mutants. Eur J Biochem 252(3):477-85 PMID:9546663
- Toke DA and Martin CE (1996) Isolation and characterization of a gene affecting fatty acid elongation in Saccharomyces cerevisiae. J Biol Chem 271(31):18413-22 PMID:8702485
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
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Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Wang Y, et al. (2024) Enhancement of ester biosynthesis in blueberry wines through co-fermentation via cell-cell contact between Torulaspora delbrueckii and Saccharomyces cerevisiae. Food Res Int 179:114029 PMID:38342548
- Xiu-Feng L, et al. (2024) Response mechanism of Saccharomyces cerevisiae under benzoic acid stress in ethanol fermentation. Sci Rep 14(1):28757 PMID:39567639
- Ding BJ, et al. (2022) Bioproduction of (Z,E)-9,12-tetradecadienyl acetate (ZETA), the major pheromone component of Plodia, Ephestia, and Spodoptera species in yeast. Pest Manag Sci 78(3):1048-1059 PMID:34773383
- Liu P, et al. (2021) Effect of Unsaturated Fatty Acids on Intra-Metabolites and Aroma Compounds of Saccharomyces cerevisiae in Wine Fermentation. Foods 10(2) PMID:33573124
- Liu PT, et al. (2019) Comparing the Effects of Different Unsaturated Fatty Acids on Fermentation Performance of Saccharomyces cerevisiae and Aroma Compounds during Red Wine Fermentation. Molecules 24(3) PMID:30717212
- Bergenholm D, et al. (2018) Modulation of saturation and chain length of fatty acids in Saccharomyces cerevisiae for production of cocoa butter-like lipids. Biotechnol Bioeng 115(4):932-942 PMID:29313898
- Yu T, et al. (2017) Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals. Nat Commun 8:15587 PMID:28548095
- Vincent M, et al. (2014) Surveying the floodgates: estimating protein flux into the endoplasmic reticulum lumen in Saccharomyces cerevisiae. Front Physiol 5:444 PMID:25431559
- Chumnanpuen P, et al. (2013) Integrated analysis, transcriptome-lipidome, reveals the effects of INO-level (INO2 and INO4) on lipid metabolism in yeast. BMC Syst Biol 7 Suppl 3(Suppl 3):S7 PMID:24456840
- Yang J, et al. (2012) Integrated phospholipidomics and transcriptomics analysis of Saccharomyces cerevisiae with enhanced tolerance to a mixture of acetic acid, furfural, and phenol. OMICS 16(7-8):374-86 PMID:22734833
- Zheng DQ, et al. (2012) Genome sequencing and genetic breeding of a bioethanol Saccharomyces cerevisiae strain YJS329. BMC Genomics 13:479 PMID:22978491
- Jung PP, et al. (2011) Ploidy influences cellular responses to gross chromosomal rearrangements in Saccharomyces cerevisiae. BMC Genomics 12:331 PMID:21711526
- Legras JL, et al. (2010) Activation of two different resistance mechanisms in Saccharomyces cerevisiae upon exposure to octanoic and decanoic acids. Appl Environ Microbiol 76(22):7526-35 PMID:20851956
- Ma M and Liu LZ (2010) Quantitative transcription dynamic analysis reveals candidate genes and key regulators for ethanol tolerance in Saccharomyces cerevisiae. BMC Microbiol 10:169 PMID:20537179
- Pedroso N, et al. (2009) Modulation of plasma membrane lipid profile and microdomains by H2O2 in Saccharomyces cerevisiae. Free Radic Biol Med 46(2):289-98 PMID:19027845
- Turunen O, et al. (2009) In silico evidence for functional specialization after genome duplication in yeast. FEMS Yeast Res 9(1):16-31 PMID:19133069
- Ponnusamy S, et al. (2008) Regulation of telomere length by fatty acid elongase 3 in yeast. Involvement of inositol phosphate metabolism and Ku70/80 function. J Biol Chem 283(41):27514-27524 PMID:18694931
- Sakuradani E, et al. (2008) Functional analysis of a fatty acid elongase from arachidonic acid-producing Mortierella alpina 1S-4. Appl Microbiol Biotechnol 81(3):497-503 PMID:18795285
- Alvarez-Vasquez F, et al. (2007) Coordination of the dynamics of yeast sphingolipid metabolism during the diauxic shift. Theor Biol Med Model 4:42 PMID:17974024
- Prasitchoke P, et al. (2007) Identification and characterization of a very long-chain fatty acid elongase gene in the methylotrophic yeast, Hansenula polymorpha. Gene 391(1-2):16-25 PMID:17236726
- Rautio JJ, et al. (2007) Monitoring yeast physiology during very high gravity wort fermentations by frequent analysis of gene expression. Yeast 24(9):741-60 PMID:17605133
- Bean JM, et al. (2005) High functional overlap between MluI cell-cycle box binding factor and Swi4/6 cell-cycle box binding factor in the G1/S transcriptional program in Saccharomyces cerevisiae. Genetics 171(1):49-61 PMID:15965243
- Gaigg B, et al. (2005) Synthesis of sphingolipids with very long chain fatty acids but not ergosterol is required for routing of newly synthesized plasma membrane ATPase to the cell surface of yeast. J Biol Chem 280(23):22515-22 PMID:15817474
- Vyas VK, et al. (2005) Repressors Nrg1 and Nrg2 regulate a set of stress-responsive genes in Saccharomyces cerevisiae. Eukaryot Cell 4(11):1882-91 PMID:16278455
- Tong AH, et al. (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13 PMID:14764870
- Agarwal AK, et al. (2003) Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae. J Biol Chem 278(37):34998-5015 PMID:12824174
- Gao J, et al. (2003) Changes in the protein expression of yeast as a function of carbon source. J Proteome Res 2(6):643-9 PMID:14692458
- Zank TK, et al. (2002) Cloning and functional characterisation of an enzyme involved in the elongation of Delta6-polyunsaturated fatty acids from the moss Physcomitrella patens. Plant J 31(3):255-68 PMID:12164806
- Beaudoin F, et al. (2000) Heterologous reconstitution in yeast of the polyunsaturated fatty acid biosynthetic pathway. Proc Natl Acad Sci U S A 97(12):6421-6 PMID:10829069
- Oh CS, et al. (1997) ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation. J Biol Chem 272(28):17376-84 PMID:9211877
Reviews
No reviews curated.
Download References (.nbib)
- Li M, et al. (2023) General mechanisms of weak acid-tolerance and current strategies for the development of tolerant yeasts. World J Microbiol Biotechnol 40(2):49 PMID:38133718
- Zhang X, et al. (2021) Developments in Fatty Acid-Derived Insect Pheromone Production Using Engineered Yeasts. Front Microbiol 12:759975 PMID:34858372
- Erdbrügger P and Fröhlich F (2020) The role of very long chain fatty acids in yeast physiology and human diseases. Biol Chem 402(1):25-38 PMID:33544487
- Wang M, et al. (2020) Advances in Metabolic Engineering of Saccharomyces cerevisiae for Cocoa Butter Equivalent Production. Front Bioeng Biotechnol 8:594081 PMID:33178680
- Fan Y, et al. (2018) Biosynthesis of nervonic acid and perspectives for its production by microalgae and other microorganisms. Appl Microbiol Biotechnol 102(7):3027-3035 PMID:29478140
- Chen Y and Nielsen J (2016) Flux control through protein phosphorylation in yeast. FEMS Yeast Res 16(8) PMID:27797916
- Klug L and Daum G (2014) Yeast lipid metabolism at a glance. FEMS Yeast Res 14(3):369-88 PMID:24520995
- Koch B, et al. (2014) Storage lipids of yeasts: a survey of nonpolar lipid metabolism in Saccharomyces cerevisiae, Pichia pastoris, and Yarrowia lipolytica. FEMS Microbiol Rev 38(5):892-915 PMID:24597968
- Montefusco DJ, et al. (2014) The yeast sphingolipid signaling landscape. Chem Phys Lipids 177:26-40 PMID:24220500
- Epstein S and Riezman H (2013) Sphingolipid signaling in yeast: potential implications for understanding disease. Front Biosci (Elite Ed) 5(1):97-108 PMID:23276973
- de Kroon AI, et al. (2013) Checks and balances in membrane phospholipid class and acyl chain homeostasis, the yeast perspective. Prog Lipid Res 52(4):374-94 PMID:23631861
- Henry SA, et al. (2012) Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae. Genetics 190(2):317-49 PMID:22345606
- Kihara A (2012) Very long-chain fatty acids: elongation, physiology and related disorders. J Biochem 152(5):387-95 PMID:22984005
- Uemura H (2012) Synthesis and production of unsaturated and polyunsaturated fatty acids in yeast: current state and perspectives. Appl Microbiol Biotechnol 95(1):1-12 PMID:22562166
- Tehlivets O, et al. (2007) Fatty acid synthesis and elongation in yeast. Biochim Biophys Acta 1771(3):255-70 PMID:16950653
- Funato K, et al. (2002) Biosynthesis and trafficking of sphingolipids in the yeast Saccharomyces cerevisiae. Biochemistry 41(51):15105-14 PMID:12484746
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Download References (.nbib)
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Rössler H, et al. (2003) Functional differentiation and selective inactivation of multiple Saccharomyces cerevisiae genes involved in very-long-chain fatty acid synthesis. Mol Genet Genomics 269(2):290-8 PMID:12684876
- Schneiter R, et al. (2000) Elo1p-dependent carboxy-terminal elongation of C14:1Delta(9) to C16:1Delta(11) fatty acids in Saccharomyces cerevisiae. J Bacteriol 182(13):3655-60 PMID:10850979
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Download References (.nbib)
- Kalli S, et al. (2023) Cellular Responses and Targets in Food Spoilage Yeasts Exposed to Antifungal Prenylated Isoflavonoids. Microbiol Spectr 11(4):e0132723 PMID:37428107
- Randez-Gil F, et al. (2020) Myriocin-induced adaptive laboratory evolution of an industrial strain of Saccharomyces cerevisiae reveals its potential to remodel lipid composition and heat tolerance. Microb Biotechnol 13(4):1066-1081 PMID:32212314
- Villasmil ML, et al. (2017) A link between very long chain fatty acid elongation and mating-specific yeast cell cycle arrest. Cell Cycle 16(22):2192-2203 PMID:28745545
- Wu X, et al. (2016) Deletion of JJJ1 improves acetic acid tolerance and bioethanol fermentation performance of Saccharomyces cerevisiae strains. Biotechnol Lett 38(7):1097-106 PMID:27067354
- Lee YJ, et al. (2011) Defects in very long chain fatty acid synthesis enhance alpha-synuclein toxicity in a yeast model of Parkinson's disease. PLoS One 6(1):e15946 PMID:21264320
- Lewis JA, et al. (2010) Exploiting natural variation in Saccharomyces cerevisiae to identify genes for increased ethanol resistance. Genetics 186(4):1197-205 PMID:20855568
- Dittrich F, et al. (1998) Fatty acid elongation in yeast--biochemical characteristics of the enzyme system and isolation of elongation-defective mutants. Eur J Biochem 252(3):477-85 PMID:9546663
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- Filali-Mouncef Y, et al. (2024) An APEX2-based proximity-dependent biotinylation assay with temporal specificity to study protein interactions during autophagy in the yeast Saccharomyces cerevisiae. Autophagy 20(10):2323-2337 PMID:38958087
- Kohler V, et al. (2024) Nuclear Hsp104 safeguards the dormant translation machinery during quiescence. Nat Commun 15(1):315 PMID:38182580
- Carey SB, et al. (2023) A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast. G3 (Bethesda) 13(1) PMID:36409020
- Michaelis AC, et al. (2023) The social and structural architecture of the yeast protein interactome. Nature 624(7990):192-200 PMID:37968396
- Perica T, et al. (2021) Systems-level effects of allosteric perturbations to a model molecular switch. Nature 599(7883):152-157 PMID:34646016
- Pereira F, et al. (2019) Effect of Sec61 interaction with Mpd1 on endoplasmic reticulum-associated degradation. PLoS One 14(1):e0211180 PMID:30682149
- Mount HO, et al. (2018) Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs. PLoS Genet 14(4):e1007319 PMID:29702647
- Opaliński Ł, et al. (2018) Recruitment of Cytosolic J-Proteins by TOM Receptors Promotes Mitochondrial Protein Biogenesis. Cell Rep 25(8):2036-2043.e5 PMID:30463002
- Lapointe CP, et al. (2017) Architecture and dynamics of overlapped RNA regulatory networks. RNA 23(11):1636-1647 PMID:28768715
- Shulist K, et al. (2017) Interrogation of γ-tubulin alleles using high-resolution fitness measurements reveals a distinct cytoplasmic function in spindle alignment. Sci Rep 7(1):11398 PMID:28900268
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Lapointe CP, et al. (2015) Protein-RNA networks revealed through covalent RNA marks. Nat Methods 12(12):1163-70 PMID:26524240
- Porter DF, et al. (2015) Target selection by natural and redesigned PUF proteins. Proc Natl Acad Sci U S A 112(52):15868-73 PMID:26668354
- Surma MA, et al. (2013) A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress. Mol Cell 51(4):519-30 PMID:23891562
- Babu M, et al. (2012) Interaction landscape of membrane-protein complexes in Saccharomyces cerevisiae. Nature 489(7417):585-9 PMID:22940862
- Moehle EA, et al. (2012) The yeast SR-like protein Npl3 links chromatin modification to mRNA processing. PLoS Genet 8(11):e1003101 PMID:23209445
- Hoppins S, et al. (2011) A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. J Cell Biol 195(2):323-40 PMID:21987634
- Szappanos B, et al. (2011) An integrated approach to characterize genetic interaction networks in yeast metabolism. Nat Genet 43(7):656-62 PMID:21623372
- Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31 PMID:20093466
- Hodge CA, et al. (2010) Integral membrane proteins Brr6 and Apq12 link assembly of the nuclear pore complex to lipid homeostasis in the endoplasmic reticulum. J Cell Sci 123(Pt 1):141-51 PMID:20016074
- Hasegawa Y, et al. (2008) Distinct roles for Khd1p in the localization and expression of bud-localized mRNAs in yeast. RNA 14(11):2333-47 PMID:18805955
- Lesage G, et al. (2005) An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae. BMC Genet 6:8 PMID:15715908
- Miller JP, et al. (2005) Large-scale identification of yeast integral membrane protein interactions. Proc Natl Acad Sci U S A 102(34):12123-8 PMID:16093310
- Ptacek J, et al. (2005) Global analysis of protein phosphorylation in yeast. Nature 438(7068):679-84 PMID:16319894
- Schuldiner M, et al. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123(3):507-19 PMID:16269340
- Tong AH, et al. (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13 PMID:14764870
- Schneiter R, et al. (2000) Elo1p-dependent carboxy-terminal elongation of C14:1Delta(9) to C16:1Delta(11) fatty acids in Saccharomyces cerevisiae. J Bacteriol 182(13):3655-60 PMID:10850979
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Michaillat L and Mayer A (2013) Identification of genes affecting vacuole membrane fragmentation in Saccharomyces cerevisiae. PLoS One 8(2):e54160 PMID:23383298
- Novo M, et al. (2013) Genome-wide study of the adaptation of Saccharomyces cerevisiae to the early stages of wine fermentation. PLoS One 8(9):e74086 PMID:24040173
- Qian W, et al. (2012) The genomic landscape and evolutionary resolution of antagonistic pleiotropy in yeast. Cell Rep 2(5):1399-410 PMID:23103169
- Svensson JP, et al. (2011) Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance. BMC Syst Biol 5:157 PMID:21978764
- Venters BJ, et al. (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92 PMID:21329885
- Ruiz-Roig C, et al. (2010) The Rpd3L HDAC complex is essential for the heat stress response in yeast. Mol Microbiol 76(4):1049-62 PMID:20398213
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Hu Z, et al. (2007) Genetic reconstruction of a functional transcriptional regulatory network. Nat Genet 39(5):683-7 PMID:17417638
- MacIsaac KD, et al. (2006) An improved map of conserved regulatory sites for Saccharomyces cerevisiae. BMC Bioinformatics 7:113 PMID:16522208
- Sopko R, et al. (2006) Mapping pathways and phenotypes by systematic gene overexpression. Mol Cell 21(3):319-30 PMID:16455487
- Lesage G, et al. (2005) An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae. BMC Genet 6:8 PMID:15715908
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549