Literature Help
RCY1 / YJL204C Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Curwin AJ, et al. (2025) The pathway of unconventional protein secretion involves CUPS and a modified trans-Golgi network. J Cell Biol 224(5) PMID:40015244
- Jiménez M, et al. (2024) P4-ATPase endosomal recycling relies on multiple retromer-dependent localization signals. Mol Biol Cell 35(10):ar125 PMID:39110530
- Kashikuma R, et al. (2023) Role of phosphatidylserine in the localization of cell surface membrane proteins in yeast. Cell Struct Funct 48(1):19-30 PMID:36517018
- Laidlaw KME, et al. (2022) Recycling of cell surface membrane proteins from yeast endosomes is regulated by ubiquitinated Ist1. J Cell Biol 221(11) PMID:36125415
- Anton-Plagaro C, et al. (2021) Exomer complex regulates protein traffic at the TGN through differential interactions with cargos and clathrin adaptor complexes. FASEB J 35(6):e21615 PMID:33978245
- Paine KM, et al. (2021) Fur4-mediated uracil-scavenging to screen for surface protein regulators. Traffic 22(11):397-408 PMID:34498791
- Best JT, et al. (2020) Yeast synaptobrevin, Snc1, engages distinct routes of postendocytic recycling mediated by a sorting nexin, Rcy1-COPI, and retromer. Mol Biol Cell 31(9):944-962 PMID:32074001
- Hoban K, et al. (2020) ESCRT-dependent protein sorting is required for the viability of yeast clathrin-mediated endocytosis mutants. Traffic 21(6):430-450 PMID:32255230
- Ma M and Burd CG (2019) Retrograde trafficking and quality control of yeast synaptobrevin, Snc1, are conferred by its transmembrane domain. Mol Biol Cell 30(14):1729-1742 PMID:31067149
- Bar-Yosef H, et al. (2017) Chemical inhibitors of Candida albicans hyphal morphogenesis target endocytosis. Sci Rep 7(1):5692 PMID:28720834
- Cheng H, et al. (2017) Multiple E3s promote the degradation of histone H3 variant Cse4. Sci Rep 7(1):8565 PMID:28819127
- MacDonald C and Piper RC (2017) Genetic dissection of early endosomal recycling highlights a TORC1-independent role for Rag GTPases. J Cell Biol 216(10):3275-3290 PMID:28768685
- Metzger MB, et al. (2017) The Ubiquitin Ligase (E3) Psh1p Is Required for Proper Segregation of both Centromeric and Two-Micron Plasmids in Saccharomyces cerevisiae. G3 (Bethesda) 7(11):3731-3743 PMID:28928274
- Xu P, et al. (2017) COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal. Elife 6 PMID:29058666
- Yamamoto T, et al. (2017) Cfs1p, a Novel Membrane Protein in the PQ-Loop Family, Is Involved in Phospholipid Flippase Functions in Yeast. G3 (Bethesda) 7(1):179-192 PMID:28057802
- Cheng H, et al. (2016) The F-box Protein Rcy1 Is Involved in the Degradation of Histone H3 Variant Cse4 and Genome Maintenance. J Biol Chem 291(19):10372-7 PMID:26975376
- Mülleder M, et al. (2016) Functional Metabolomics Describes the Yeast Biosynthetic Regulome. Cell 167(2):553-565.e12 PMID:27693354
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Garay E, et al. (2014) High-resolution profiling of stationary-phase survival reveals yeast longevity factors and their genetic interactions. PLoS Genet 10(2):e1004168 PMID:24586198
- Hanamatsu H, et al. (2014) Interaction of the phospholipid flippase Drs2p with the F-box protein Rcy1p plays an important role in early endosome to trans-Golgi network vesicle transport in yeast. J Biochem 155(1):51-62 PMID:24272750
- Yibmantasiri P, et al. (2014) Networks of genes modulating the pleiotropic drug response in Saccharomyces cerevisiae. Mol Biosyst 10(1):128-37 PMID:24201294
- Sukhai MA, et al. (2013) Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors. J Clin Invest 123(1):315-28 PMID:23202731
- Sun Y and Drubin DG (2012) The functions of anionic phospholipids during clathrin-mediated endocytosis site initiation and vesicle formation. J Cell Sci 125(Pt 24):6157-65 PMID:23097040
- Chen SH, et al. (2011) Ypt31/32 GTPases and their F-Box effector Rcy1 regulate ubiquitination of recycling proteins. Cell Logist 1(1):21-31 PMID:21686101
- Lim MK, et al. (2011) Galactose induction of the GAL1 gene requires conditional degradation of the Mig2 repressor. Biochem J 435(3):641-9 PMID:21323640
- Jacquier N and Schneiter R (2010) Ypk1, the yeast orthologue of the human serum- and glucocorticoid-induced kinase, is required for efficient uptake of fatty acids. J Cell Sci 123(Pt 13):2218-27 PMID:20516150
- Kato M, et al. (2010) Remodeling of the SCF complex-mediated ubiquitination system by compositional alteration of incorporated F-box proteins. Proteomics 10(1):115-23 PMID:19882662
- Ottosson LG, et al. (2010) Sulfate assimilation mediates tellurite reduction and toxicity in Saccharomyces cerevisiae. Eukaryot Cell 9(10):1635-47 PMID:20675578
- Riechers SP, et al. (2010) Endocytic uptake of fluorescence labelled DNA in yeast. J Basic Microbiol 50(1):83-9 PMID:20175124
- Gustavsson M, et al. (2008) Functional genomics of monensin sensitivity in yeast: implications for post-Golgi traffic and vacuolar H+-ATPase function. Mol Genet Genomics 280(3):233-48 PMID:18612650
- Furuta N, et al. (2007) Endocytic recycling in yeast is regulated by putative phospholipid translocases and the Ypt31p/32p-Rcy1p pathway. Mol Biol Cell 18(1):295-312 PMID:17093059
- Pagani MA, et al. (2007) Disruption of iron homeostasis in Saccharomyces cerevisiae by high zinc levels: a genome-wide study. Mol Microbiol 65(2):521-37 PMID:17630978
- Chen SH, et al. (2005) Ypt31/32 GTPases and their novel F-box effector protein Rcy1 regulate protein recycling. Mol Biol Cell 16(1):178-92 PMID:15537705
- Lafourcade C, et al. (2003) Opposite roles of the F-box protein Rcy1p and the GTPase-activating protein Gyp2p during recycling of internalized proteins in yeast. Genetics 164(2):469-77 PMID:12807768
- Galan JM, et al. (2001) Skp1p and the F-box protein Rcy1p form a non-SCF complex involved in recycling of the SNARE Snc1p in yeast. Mol Cell Biol 21(9):3105-17 PMID:11287615
- Murén E, et al. (2001) Identification of yeast deletion strains that are hypersensitive to brefeldin A or monensin, two drugs that affect intracellular transport. Yeast 18(2):163-72 PMID:11169758
- Wiederkehr A, et al. (2001) Identification and characterization of Saccharomyces cerevisiae mutants defective in fluid-phase endocytosis. Yeast 18(8):759-73 PMID:11378903
- de Groot PW, et al. (2001) A genomic approach for the identification and classification of genes involved in cell wall formation and its regulation in Saccharomyces cerevisiae. Comp Funct Genomics 2(3):124-42 PMID:18628907
- Wiederkehr A, et al. (2000) The F-box protein Rcy1p is involved in endocytic membrane traffic and recycling out of an early endosome in Saccharomyces cerevisiae. J Cell Biol 149(2):397-410 PMID:10769031
- Wysocki R, et al. (1999) Disruption and basic phenotypic analysis of 18 novel genes from the yeast Saccharomyces cerevisiae. Yeast 15(2):165-71 PMID:10029995
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
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Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Laidlaw KME, et al. (2022) Endosomal cargo recycling mediated by Gpa1 and phosphatidylinositol 3-kinase is inhibited by glucose starvation. Mol Biol Cell 33(4):ar31 PMID:35080991
- Amoiradaki K, et al. (2021) The Rpd3-Complex Regulates Expression of Multiple Cell Surface Recycling Factors in Yeast. Int J Mol Sci 22(22) PMID:34830359
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Eisenberg-Bord M, et al. (2018) Identification of seipin-linked factors that act as determinants of a lipid droplet subpopulation. J Cell Biol 217(1):269-282 PMID:29187527
- D'Angelo F, et al. (2013) A yeast model for amyloid-β aggregation exemplifies the role of membrane trafficking and PICALM in cytotoxicity. Dis Model Mech 6(1):206-16 PMID:22888099
- Lukehart J, et al. (2013) Vps1, a recycling factor for the traffic from early endosome to the late Golgi. Biochem Cell Biol 91(6):455-65 PMID:24219288
- Mukherjee D, et al. (2013) Bem3, a Cdc42 GTPase-activating protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes. J Cell Sci 126(Pt 20):4560-71 PMID:23943876
- Tsujimoto Y, et al. (2013) Functional roles of YPT31 and YPT32 in clotrimazole resistance of Saccharomyces cerevisiae through effects on vacuoles and ATP-binding cassette transporter(s). J Biosci Bioeng 115(1):4-11 PMID:22999853
- Hoepfner D, et al. (2012) An integrated approach for identification and target validation of antifungal compounds active against Erg11p. Antimicrob Agents Chemother 56(8):4233-40 PMID:22615293
- Barreto L, et al. (2011) A genomewide screen for tolerance to cationic drugs reveals genes important for potassium homeostasis in Saccharomyces cerevisiae. Eukaryot Cell 10(9):1241-50 PMID:21724935
- Gordon JL, et al. (2011) Evolutionary erosion of yeast sex chromosomes by mating-type switching accidents. Proc Natl Acad Sci U S A 108(50):20024-9 PMID:22123960
- Jung PP, et al. (2011) Ploidy influences cellular responses to gross chromosomal rearrangements in Saccharomyces cerevisiae. BMC Genomics 12:331 PMID:21711526
- Soper JH, et al. (2011) Aggregation of α-synuclein in S. cerevisiae is associated with defects in endosomal trafficking and phospholipid biosynthesis. J Mol Neurosci 43(3):391-405 PMID:20890676
- Villa-García MJ, et al. (2011) Genome-wide screen for inositol auxotrophy in Saccharomyces cerevisiae implicates lipid metabolism in stress response signaling. Mol Genet Genomics 285(2):125-49 PMID:21136082
- Logsdon BA and Mezey J (2010) Gene expression network reconstruction by convex feature selection when incorporating genetic perturbations. PLoS Comput Biol 6(12):e1001014 PMID:21152011
- Venancio TM, et al. (2010) Robustness and evolvability in natural chemical resistance: identification of novel systems properties, biochemical mechanisms and regulatory interactions. Mol Biosyst 6(8):1475-91 PMID:20517567
- Kim JH, et al. (2009) The unfolded protein response is necessary but not sufficient to compensate for defects in disulfide isomerization. J Biol Chem 284(16):10400-8 PMID:19233841
- Poole K, et al. (2009) Proline transport and stress tolerance of ammonia-insensitive mutants of the PUT4-encoded proline-specific permease in yeast. J Gen Appl Microbiol 55(6):427-39 PMID:20118607
- Riechers SP, et al. (2009) Defects in intracellular trafficking and endocytic/vacuolar acidification determine the efficiency of endocytotic DNA uptake in yeast. J Cell Biochem 106(2):327-36 PMID:19115284
- Herrero AB, et al. (2008) Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734. Cancer Res 68(23):9779-87 PMID:19047157
- Liu K, et al. (2008) P4-ATPase requirement for AP-1/clathrin function in protein transport from the trans-Golgi network and early endosomes. Mol Biol Cell 19(8):3526-35 PMID:18508916
- Mutiu AI, et al. (2007) Structure/function analysis of the phosphatidylinositol-3-kinase domain of yeast tra1. Genetics 177(1):151-66 PMID:17660562
- Nakanishi H, et al. (2007) Erv14 family cargo receptors are necessary for ER exit during sporulation in Saccharomyces cerevisiae. J Cell Sci 120(Pt 5):908-16 PMID:17298976
- Thevissen K, et al. (2007) Miconazole induces changes in actin cytoskeleton prior to reactive oxygen species induction in yeast. J Biol Chem 282(30):21592-7 PMID:17553796
- Hwang GW, et al. (2006) Identification of F-box proteins that are involved in resistance to methylmercury in Saccharomyces cerevisiae. FEBS Lett 580(30):6813-8 PMID:17141224
- Tagwerker C, et al. (2006) A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking. Mol Cell Proteomics 5(4):737-48 PMID:16432255
- Kus BM, et al. (2004) Functional interaction of 13 yeast SCF complexes with a set of yeast E2 enzymes in vitro. Proteins 54(3):455-67 PMID:14747994
- Enyenihi AH and Saunders WS (2003) Large-scale functional genomic analysis of sporulation and meiosis in Saccharomyces cerevisiae. Genetics 163(1):47-54 PMID:12586695
- Gupta SS, et al. (2003) Antifungal activity of amiodarone is mediated by disruption of calcium homeostasis. J Biol Chem 278(31):28831-9 PMID:12754197
- Kushner DB, et al. (2003) Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Proc Natl Acad Sci U S A 100(26):15764-9 PMID:14671320
- Avaro S, et al. (2002) Mutants defective in secretory/vacuolar pathways in the EUROFAN collection of yeast disruptants. Yeast 19(4):351-71 PMID:11870858
- Higgins VJ, et al. (2002) Phenotypic analysis of gene deletant strains for sensitivity to oxidative stress. Yeast 19(3):203-14 PMID:11816028
- Seol JH, et al. (2001) Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly. Nat Cell Biol 3(4):384-91 PMID:11283612
- Rieger KJ, et al. (1999) Chemotyping of yeast mutants using robotics. Yeast 15(10B):973-86 PMID:10407277
- Willems AR, et al. (1999) SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis. Philos Trans R Soc Lond B Biol Sci 354(1389):1533-50 PMID:10582239
Reviews
No reviews curated.
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Download References (.nbib)
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Hanamatsu H, et al. (2014) Interaction of the phospholipid flippase Drs2p with the F-box protein Rcy1p plays an important role in early endosome to trans-Golgi network vesicle transport in yeast. J Biochem 155(1):51-62 PMID:24272750
- Chen SH, et al. (2005) Ypt31/32 GTPases and their novel F-box effector protein Rcy1 regulate protein recycling. Mol Biol Cell 16(1):178-92 PMID:15537705
- Galan JM, et al. (2001) Skp1p and the F-box protein Rcy1p form a non-SCF complex involved in recycling of the SNARE Snc1p in yeast. Mol Cell Biol 21(9):3105-17 PMID:11287615
- Wiederkehr A, et al. (2001) Identification and characterization of Saccharomyces cerevisiae mutants defective in fluid-phase endocytosis. Yeast 18(8):759-73 PMID:11378903
- Wiederkehr A, et al. (2000) The F-box protein Rcy1p is involved in endocytic membrane traffic and recycling out of an early endosome in Saccharomyces cerevisiae. J Cell Biol 149(2):397-410 PMID:10769031
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Download References (.nbib)
- Kashikuma R, et al. (2023) Role of phosphatidylserine in the localization of cell surface membrane proteins in yeast. Cell Struct Funct 48(1):19-30 PMID:36517018
- Laidlaw KME, et al. (2022) Recycling of cell surface membrane proteins from yeast endosomes is regulated by ubiquitinated Ist1. J Cell Biol 221(11) PMID:36125415
- Anton-Plagaro C, et al. (2021) Exomer complex regulates protein traffic at the TGN through differential interactions with cargos and clathrin adaptor complexes. FASEB J 35(6):e21615 PMID:33978245
- Best JT, et al. (2020) Yeast synaptobrevin, Snc1, engages distinct routes of postendocytic recycling mediated by a sorting nexin, Rcy1-COPI, and retromer. Mol Biol Cell 31(9):944-962 PMID:32074001
- Cao C, et al. (2020) Genome-wide identification for genes involved in sodium dodecyl sulfate toxicity in Saccharomyces cerevisiae. BMC Microbiol 20(1):34 PMID:32066383
- Zhao YY, et al. (2020) Genetic analysis of oxidative and endoplasmic reticulum stress responses induced by cobalt toxicity in budding yeast. Biochim Biophys Acta Gen Subj 1864(3):129516 PMID:31904504
- Bar-Yosef H, et al. (2017) Chemical inhibitors of Candida albicans hyphal morphogenesis target endocytosis. Sci Rep 7(1):5692 PMID:28720834
- Yamamoto T, et al. (2017) Cfs1p, a Novel Membrane Protein in the PQ-Loop Family, Is Involved in Phospholipid Flippase Functions in Yeast. G3 (Bethesda) 7(1):179-192 PMID:28057802
- Garay E, et al. (2014) High-resolution profiling of stationary-phase survival reveals yeast longevity factors and their genetic interactions. PLoS Genet 10(2):e1004168 PMID:24586198
- Sun Y and Drubin DG (2012) The functions of anionic phospholipids during clathrin-mediated endocytosis site initiation and vesicle formation. J Cell Sci 125(Pt 24):6157-65 PMID:23097040
- Ottosson LG, et al. (2010) Sulfate assimilation mediates tellurite reduction and toxicity in Saccharomyces cerevisiae. Eukaryot Cell 9(10):1635-47 PMID:20675578
- Riechers SP, et al. (2010) Endocytic uptake of fluorescence labelled DNA in yeast. J Basic Microbiol 50(1):83-9 PMID:20175124
- Gustavsson M, et al. (2008) Functional genomics of monensin sensitivity in yeast: implications for post-Golgi traffic and vacuolar H+-ATPase function. Mol Genet Genomics 280(3):233-48 PMID:18612650
- Pagani MA, et al. (2007) Disruption of iron homeostasis in Saccharomyces cerevisiae by high zinc levels: a genome-wide study. Mol Microbiol 65(2):521-37 PMID:17630978
- de Groot PW, et al. (2001) A genomic approach for the identification and classification of genes involved in cell wall formation and its regulation in Saccharomyces cerevisiae. Comp Funct Genomics 2(3):124-42 PMID:18628907
- Murén E, et al. (2001) Identification of yeast deletion strains that are hypersensitive to brefeldin A or monensin, two drugs that affect intracellular transport. Yeast 18(2):163-72 PMID:11169758
- Wysocki R, et al. (1999) Disruption and basic phenotypic analysis of 18 novel genes from the yeast Saccharomyces cerevisiae. Yeast 15(2):165-71 PMID:10029995
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- Jiménez M, et al. (2024) P4-ATPase endosomal recycling relies on multiple retromer-dependent localization signals. Mol Biol Cell 35(10):ar125 PMID:39110530
- O'Brien MJ and Ansari A (2024) Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle. Biochim Biophys Acta Proteins Proteom 1872(1):140968 PMID:37863410
- Carey SB, et al. (2023) A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast. G3 (Bethesda) 13(1) PMID:36409020
- Cohen N, et al. (2023) A systematic proximity ligation approach to studying protein-substrate specificity identifies the substrate spectrum of the Ssh1 translocon. EMBO J 42(11):e113385 PMID:37073826
- Michaelis AC, et al. (2023) The social and structural architecture of the yeast protein interactome. Nature 624(7990):192-200 PMID:37968396
- Smurova K, et al. (2023) Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores. Nat Commun 14(1):3172 PMID:37263996
- Mattingly M, et al. (2022) Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion. Curr Biol 32(13):2884-2896.e6 PMID:35654035
- Anton-Plagaro C, et al. (2021) Exomer complex regulates protein traffic at the TGN through differential interactions with cargos and clathrin adaptor complexes. FASEB J 35(6):e21615 PMID:33978245
- Best JT, et al. (2020) Yeast synaptobrevin, Snc1, engages distinct routes of postendocytic recycling mediated by a sorting nexin, Rcy1-COPI, and retromer. Mol Biol Cell 31(9):944-962 PMID:32074001
- Hoban K, et al. (2020) ESCRT-dependent protein sorting is required for the viability of yeast clathrin-mediated endocytosis mutants. Traffic 21(6):430-450 PMID:32255230
- Lari A, et al. (2019) A nuclear role for the DEAD-box protein Dbp5 in tRNA export. Elife 8 PMID:31453808
- Ma M and Burd CG (2019) Retrograde trafficking and quality control of yeast synaptobrevin, Snc1, are conferred by its transmembrane domain. Mol Biol Cell 30(14):1729-1742 PMID:31067149
- Miller JE, et al. (2018) Genome-Wide Mapping of Decay Factor-mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4. G3 (Bethesda) 8(1):315-330 PMID:29158339
- Böckler S, et al. (2017) Fusion, fission, and transport control asymmetric inheritance of mitochondria and protein aggregates. J Cell Biol 216(8):2481-2498 PMID:28615194
- Cheng H, et al. (2017) Multiple E3s promote the degradation of histone H3 variant Cse4. Sci Rep 7(1):8565 PMID:28819127
- Jungfleisch J, et al. (2017) A novel translational control mechanism involving RNA structures within coding sequences. Genome Res 27(1):95-106 PMID:27821408
- Lawrence MBD, et al. (2017) Histone Acetylation, Not Stoichiometry, Regulates Linker Histone Binding in Saccharomyces cerevisiae. Genetics 207(1):347-355 PMID:28739661
- Yamamoto T, et al. (2017) Cfs1p, a Novel Membrane Protein in the PQ-Loop Family, Is Involved in Phospholipid Flippase Functions in Yeast. G3 (Bethesda) 7(1):179-192 PMID:28057802
- Zimmermann C, et al. (2017) Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28. G3 (Bethesda) 7(6):1753-1766 PMID:28428242
- Cheng H, et al. (2016) The F-box Protein Rcy1 Is Involved in the Degradation of Histone H3 Variant Cse4 and Genome Maintenance. J Biol Chem 291(19):10372-7 PMID:26975376
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Kyriakou D, et al. (2016) Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae. BMC Biol 14(1):106 PMID:27927215
- Imamura Y, et al. (2015) RSC Chromatin-Remodeling Complex Is Important for Mitochondrial Function in Saccharomyces cerevisiae. PLoS One 10(6):e0130397 PMID:26086550
- Lapointe CP, et al. (2015) Protein-RNA networks revealed through covalent RNA marks. Nat Methods 12(12):1163-70 PMID:26524240
- Figley MD, et al. (2014) Profilin 1 associates with stress granules and ALS-linked mutations alter stress granule dynamics. J Neurosci 34(24):8083-97 PMID:24920614
- Hanamatsu H, et al. (2014) Interaction of the phospholipid flippase Drs2p with the F-box protein Rcy1p plays an important role in early endosome to trans-Golgi network vesicle transport in yeast. J Biochem 155(1):51-62 PMID:24272750
- Yibmantasiri P, et al. (2014) Networks of genes modulating the pleiotropic drug response in Saccharomyces cerevisiae. Mol Biosyst 10(1):128-37 PMID:24201294
- Lai X, et al. (2013) Yeast hEST1A/B (SMG5/6)-like proteins contribute to environment-sensing adaptive gene expression responses. G3 (Bethesda) 3(10):1649-59 PMID:23893744
- Lukehart J, et al. (2013) Vps1, a recycling factor for the traffic from early endosome to the late Golgi. Biochem Cell Biol 91(6):455-65 PMID:24219288
- van Pel DM, et al. (2013) Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork. G3 (Bethesda) 3(2):273-82 PMID:23390603
- Zemla A, et al. (2013) CSN- and CAND1-dependent remodelling of the budding yeast SCF complex. Nat Commun 4:1641 PMID:23535662
- Darby MM, et al. (2012) The Saccharomyces cerevisiae Nrd1-Nab3 transcription termination pathway acts in opposition to Ras signaling and mediates response to nutrient depletion. Mol Cell Biol 32(10):1762-75 PMID:22431520
- Gilmore JM, et al. (2012) Characterization of a highly conserved histone related protein, Ydl156w, and its functional associations using quantitative proteomic analyses. Mol Cell Proteomics 11(4):M111.011544 PMID:22199229
- Kojima A, et al. (2012) Localization and functional requirement of yeast Na+/H+ exchanger, Nhx1p, in the endocytic and protein recycling pathway. Biochim Biophys Acta 1823(2):534-43 PMID:22210050
- Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801 PMID:22282571
- Yen JL, et al. (2012) Signal-induced disassembly of the SCF ubiquitin ligase complex by Cdc48/p97. Mol Cell 48(2):288-97 PMID:23000173
- Chen SH, et al. (2011) Ypt31/32 GTPases and their F-Box effector Rcy1 regulate ubiquitination of recycling proteins. Cell Logist 1(1):21-31 PMID:21686101
- Finnigan GC, et al. (2011) A genome-wide enhancer screen implicates sphingolipid composition in vacuolar ATPase function in Saccharomyces cerevisiae. Genetics 187(3):771-83 PMID:21196517
- León Ortiz AM, et al. (2011) Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functions. DNA Repair (Amst) 10(5):506-17 PMID:21459050
- Stirling PC, et al. (2011) The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components. PLoS Genet 7(4):e1002057 PMID:21552543
- Kim JH, et al. (2009) The unfolded protein response is necessary but not sufficient to compensate for defects in disulfide isomerization. J Biol Chem 284(16):10400-8 PMID:19233841
- Dekker C, et al. (2008) The interaction network of the chaperonin CCT. EMBO J 27(13):1827-39 PMID:18511909
- Gustavsson M, et al. (2008) Functional genomics of monensin sensitivity in yeast: implications for post-Golgi traffic and vacuolar H+-ATPase function. Mol Genet Genomics 280(3):233-48 PMID:18612650
- Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74 PMID:18676811
- Mousley CJ, et al. (2008) Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast. Mol Biol Cell 19(11):4785-803 PMID:18753406
- Schöner D, et al. (2008) Annotating novel genes by integrating synthetic lethals and genomic information. BMC Syst Biol 2:3 PMID:18194531
- Zhao R, et al. (2008) Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation. J Cell Biol 180(3):563-78 PMID:18268103
- Furuta N, et al. (2007) Endocytic recycling in yeast is regulated by putative phospholipid translocases and the Ypt31p/32p-Rcy1p pathway. Mol Biol Cell 18(1):295-312 PMID:17093059
- Haarer B, et al. (2007) Modeling complex genetic interactions in a simple eukaryotic genome: actin displays a rich spectrum of complex haploinsufficiencies. Genes Dev 21(2):148-59 PMID:17167106
- McClellan AJ, et al. (2007) Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches. Cell 131(1):121-35 PMID:17923092
- Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 PMID:16487579
- Tagwerker C, et al. (2006) A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking. Mol Cell Proteomics 5(4):737-48 PMID:16432255
- Chen SH, et al. (2005) Ypt31/32 GTPases and their novel F-box effector protein Rcy1 regulate protein recycling. Mol Biol Cell 16(1):178-92 PMID:15537705
- Kishimoto T, et al. (2005) Defects in structural integrity of ergosterol and the Cdc50p-Drs2p putative phospholipid translocase cause accumulation of endocytic membranes, onto which actin patches are assembled in yeast. Mol Biol Cell 16(12):5592-609 PMID:16195350
- Kus BM, et al. (2004) Functional interaction of 13 yeast SCF complexes with a set of yeast E2 enzymes in vitro. Proteins 54(3):455-67 PMID:14747994
- Lafourcade C, et al. (2003) Opposite roles of the F-box protein Rcy1p and the GTPase-activating protein Gyp2p during recycling of internalized proteins in yeast. Genetics 164(2):469-77 PMID:12807768
- Galan JM, et al. (2001) Skp1p and the F-box protein Rcy1p form a non-SCF complex involved in recycling of the SNARE Snc1p in yeast. Mol Cell Biol 21(9):3105-17 PMID:11287615
- Seol JH, et al. (2001) Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly. Nat Cell Biol 3(4):384-91 PMID:11283612
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
Download References (.nbib)
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Zhou X, et al. (2021) Cross-compartment signal propagation in the mitotic exit network. Elife 10 PMID:33481703
- Chen YC, et al. (2018) Glucose intake hampers PKA-regulated HSP90 chaperone activity. Elife 7 PMID:30516470
- Swaney DL, et al. (2013) Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nat Methods 10(7):676-82 PMID:23749301
- Holt LJ, et al. (2009) Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution. Science 325(5948):1682-6 PMID:19779198
- Albuquerque CP, et al. (2008) A multidimensional chromatography technology for in-depth phosphoproteome analysis. Mol Cell Proteomics 7(7):1389-96 PMID:18407956
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Grosjean N, et al. (2023) Yeast Deletomics to Uncover Gadolinium Toxicity Targets and Resistance Mechanisms. Microorganisms 11(8) PMID:37630673
- Pallares RM, et al. (2022) Identifying Toxicity Mechanisms Associated with Early Lanthanide Exposure through Multidimensional Genome-Wide Screening. ACS Omega 7(38):34412-34419 PMID:36188298
- Jin X, et al. (2021) Retromer Complex and PI3K Complex II-Related Genes Mediate the Yeast (Saccharomyces cerevisiae) Sodium Metabisulfite Resistance Response. Cells 10(12) PMID:34944020
- Papagiannidis D, et al. (2021) Ice2 promotes ER membrane biogenesis in yeast by inhibiting the conserved lipin phosphatase complex. EMBO J 40(22):e107958 PMID:34617598
- Rossignol T, et al. (2021) Ethylzingerone, a Novel Compound with Antifungal Activity. Antimicrob Agents Chemother 65(4) PMID:33468481
- Baruffini E, et al. (2020) Mechanistic insights on the mode of action of an antiproliferative thiosemicarbazone-nickel complex revealed by an integrated chemogenomic profiling study. Sci Rep 10(1):10524 PMID:32601343
- Cao C, et al. (2020) Genome-wide identification for genes involved in sodium dodecyl sulfate toxicity in Saccharomyces cerevisiae. BMC Microbiol 20(1):34 PMID:32066383
- Helsen J, et al. (2020) Gene Loss Predictably Drives Evolutionary Adaptation. Mol Biol Evol 37(10):2989-3002 PMID:32658971
- Zhao YY, et al. (2020) Genetic analysis of oxidative and endoplasmic reticulum stress responses induced by cobalt toxicity in budding yeast. Biochim Biophys Acta Gen Subj 1864(3):129516 PMID:31904504
- Zhao YY, et al. (2020) Identification of the Genetic Requirements for Zinc Tolerance and Toxicity in Saccharomyces cerevisiae. G3 (Bethesda) 10(2):479-488 PMID:31836620
- Eisenberg-Bord M, et al. (2018) Identification of seipin-linked factors that act as determinants of a lipid droplet subpopulation. J Cell Biol 217(1):269-282 PMID:29187527
- Grosjean N, et al. (2018) Global Deletome Profile of Saccharomyces cerevisiae Exposed to the Technology-Critical Element Yttrium. Front Microbiol 9:2005 PMID:30233513
- Henriques SF, et al. (2017) Genome-wide search for candidate genes for yeast robustness improvement against formic acid reveals novel susceptibility (Trk1 and positive regulators) and resistance (Haa1-regulon) determinants. Biotechnol Biofuels 10:96 PMID:28428821
- Khurana V, et al. (2017) Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways. Cell Syst 4(2):157-170.e14 PMID:28131822
- Mülleder M, et al. (2016) Functional Metabolomics Describes the Yeast Biosynthetic Regulome. Cell 167(2):553-565.e12 PMID:27693354
- Fröhlich F, et al. (2015) The GARP complex is required for cellular sphingolipid homeostasis. Elife 4 PMID:26357016
- García R, et al. (2015) Genomic profiling of fungal cell wall-interfering compounds: identification of a common gene signature. BMC Genomics 16(1):683 PMID:26341223
- Hendry JA, et al. (2015) Leveraging DNA damage response signaling to identify yeast genes controlling genome stability. G3 (Bethesda) 5(5):997-1006 PMID:25721128
- Krol K, et al. (2015) A genomic screen revealing the importance of vesicular trafficking pathways in genome maintenance and protection against genotoxic stress in diploid Saccharomyces cerevisiae cells. PLoS One 10(3):e0120702 PMID:25756177
- Zhu J, et al. (2015) Single-Cell Based Quantitative Assay of Chromosome Transmission Fidelity. G3 (Bethesda) 5(6):1043-56 PMID:25823586
- Garay E, et al. (2014) High-resolution profiling of stationary-phase survival reveals yeast longevity factors and their genetic interactions. PLoS Genet 10(2):e1004168 PMID:24586198
- Gaupel AC, et al. (2014) High throughput screening identifies modulators of histone deacetylase inhibitors. BMC Genomics 15(1):528 PMID:24968945
- Hoepfner D, et al. (2014) High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions. Microbiol Res 169(2-3):107-20 PMID:24360837
- Schlecht U, et al. (2014) A functional screen for copper homeostasis genes identifies a pharmacologically tractable cellular system. BMC Genomics 15:263 PMID:24708151
- Cuesta-Marbán Á, et al. (2013) Drug uptake, lipid rafts, and vesicle trafficking modulate resistance to an anticancer lysophosphatidylcholine analogue in yeast. J Biol Chem 288(12):8405-8418 PMID:23335509
- Jarolim S, et al. (2013) Saccharomyces cerevisiae genes involved in survival of heat shock. G3 (Bethesda) 3(12):2321-33 PMID:24142923
- Marek A and Korona R (2013) Restricted pleiotropy facilitates mutational erosion of major life-history traits. Evolution 67(11):3077-86 PMID:24151994
- Michaillat L and Mayer A (2013) Identification of genes affecting vacuole membrane fragmentation in Saccharomyces cerevisiae. PLoS One 8(2):e54160 PMID:23383298
- Shively CA, et al. (2013) Genetic networks inducing invasive growth in Saccharomyces cerevisiae identified through systematic genome-wide overexpression. Genetics 193(4):1297-310 PMID:23410832
- Sukhai MA, et al. (2013) Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors. J Clin Invest 123(1):315-28 PMID:23202731
- Huang Z, et al. (2012) Discovering thiamine transporters as targets of chloroquine using a novel functional genomics strategy. PLoS Genet 8(11):e1003083 PMID:23209439
- Kim H, et al. (2012) Vacuolar H+-ATPase (V-ATPase) promotes vacuolar membrane permeabilization and nonapoptotic death in stressed yeast. J Biol Chem 287(23):19029-39 PMID:22511765
- North M, et al. (2012) Genome-wide functional profiling identifies genes and processes important for zinc-limited growth of Saccharomyces cerevisiae. PLoS Genet 8(6):e1002699 PMID:22685415
- Peyroche G, et al. (2012) Sodium selenide toxicity is mediated by O2-dependent DNA breaks. PLoS One 7(5):e36343 PMID:22586468
- Pir P, et al. (2012) The genetic control of growth rate: a systems biology study in yeast. BMC Syst Biol 6:4 PMID:22244311
- Qian W, et al. (2012) The genomic landscape and evolutionary resolution of antagonistic pleiotropy in yeast. Cell Rep 2(5):1399-410 PMID:23103169
- Servienė E, et al. (2012) Screening the budding yeast genome reveals unique factors affecting K2 toxin susceptibility. PLoS One 7(12):e50779 PMID:23227207
- Yu D, et al. (2012) High-resolution genome-wide scan of genes, gene-networks and cellular systems impacting the yeast ionome. BMC Genomics 13:623 PMID:23151179
- Barreto L, et al. (2011) A genomewide screen for tolerance to cationic drugs reveals genes important for potassium homeostasis in Saccharomyces cerevisiae. Eukaryot Cell 10(9):1241-50 PMID:21724935
- Bleackley MR, et al. (2011) High density array screening to identify the genetic requirements for transition metal tolerance in Saccharomyces cerevisiae. Metallomics 3(2):195-205 PMID:21212869
- Dos Santos SC and Sá-Correia I (2011) A genome-wide screen identifies yeast genes required for protection against or enhanced cytotoxicity of the antimalarial drug quinine. Mol Genet Genomics 286(5-6):333-46 PMID:21960436
- Ratnakumar S, et al. (2011) Phenomic and transcriptomic analyses reveal that autophagy plays a major role in desiccation tolerance in Saccharomyces cerevisiae. Mol Biosyst 7(1):139-49 PMID:20963216
- Svensson JP, et al. (2011) Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance. BMC Syst Biol 5:157 PMID:21978764
- Venters BJ, et al. (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92 PMID:21329885
- Villa-García MJ, et al. (2011) Genome-wide screen for inositol auxotrophy in Saccharomyces cerevisiae implicates lipid metabolism in stress response signaling. Mol Genet Genomics 285(2):125-49 PMID:21136082
- Yoshikawa K, et al. (2011) Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28(5):349-61 PMID:21341307
- Batova M, et al. (2010) Chemogenomic and transcriptome analysis identifies mode of action of the chemosensitizing agent CTBT (7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine). BMC Genomics 11:153 PMID:20202201
- Holbein S, et al. (2009) Cordycepin interferes with 3' end formation in yeast independently of its potential to terminate RNA chain elongation. RNA 15(5):837-49 PMID:19324962
- Jo WJ, et al. (2009) Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae. BMC Genomics 10:130 PMID:19321002
- Kemmer D, et al. (2009) Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis. BMC Microbiol 9:9 PMID:19144191
- Mira NP, et al. (2009) The RIM101 pathway has a role in Saccharomyces cerevisiae adaptive response and resistance to propionic acid and other weak acids. FEMS Yeast Res 9(2):202-16 PMID:19220866
- Teixeira MC, et al. (2009) Genome-wide identification of Saccharomyces cerevisiae genes required for maximal tolerance to ethanol. Appl Environ Microbiol 75(18):5761-72 PMID:19633105
- Watanabe M, et al. (2009) Comprehensive and quantitative analysis of yeast deletion mutants defective in apical and isotropic bud growth. Curr Genet 55(4):365-80 PMID:19466415
- Zhou X, et al. (2009) A genome-wide screen in Saccharomyces cerevisiae reveals pathways affected by arsenic toxicity. Genomics 94(5):294-307 PMID:19631266
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Gustavsson M, et al. (2008) Functional genomics of monensin sensitivity in yeast: implications for post-Golgi traffic and vacuolar H+-ATPase function. Mol Genet Genomics 280(3):233-48 PMID:18612650
- Herrero AB, et al. (2008) Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734. Cancer Res 68(23):9779-87 PMID:19047157
- Sinha H, et al. (2008) Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast. Genetics 180(3):1661-70 PMID:18780730
- Yu L, et al. (2008) Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells. PLoS Genet 4(11):e1000284 PMID:19043571
- Thevissen K, et al. (2007) Miconazole induces changes in actin cytoskeleton prior to reactive oxygen species induction in yeast. J Biol Chem 282(30):21592-7 PMID:17553796
- Yadav J, et al. (2007) A phenomics approach in yeast links proton and calcium pump function in the Golgi. Mol Biol Cell 18(4):1480-9 PMID:17314395
- Brown JA, et al. (2006) Global analysis of gene function in yeast by quantitative phenotypic profiling. Mol Syst Biol 2:2006.0001 PMID:16738548
- Kawahata M, et al. (2006) Yeast genes involved in response to lactic acid and acetic acid: acidic conditions caused by the organic acids in Saccharomyces cerevisiae cultures induce expression of intracellular metal metabolism genes regulated by Aft1p. FEMS Yeast Res 6(6):924-36 PMID:16911514
- Deutschbauer AM, et al. (2005) Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast. Genetics 169(4):1915-25 PMID:15716499
- Dudley AM, et al. (2005) A global view of pleiotropy and phenotypically derived gene function in yeast. Mol Syst Biol 1:2005.0001 PMID:16729036
- Aouida M, et al. (2004) A genome-wide screen in Saccharomyces cerevisiae reveals altered transport as a mechanism of resistance to the anticancer drug bleomycin. Cancer Res 64(3):1102-9 PMID:14871844
- Lesage G, et al. (2004) Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin. Genetics 167(1):35-49 PMID:15166135
- Lum PY, et al. (2004) Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell 116(1):121-37 PMID:14718172
- Parsons AB, et al. (2004) Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nat Biotechnol 22(1):62-9 PMID:14661025
- Enyenihi AH and Saunders WS (2003) Large-scale functional genomic analysis of sporulation and meiosis in Saccharomyces cerevisiae. Genetics 163(1):47-54 PMID:12586695
- Gupta SS, et al. (2003) Antifungal activity of amiodarone is mediated by disruption of calcium homeostasis. J Biol Chem 278(31):28831-9 PMID:12754197
- Desmoucelles C, et al. (2002) Screening the yeast "disruptome" for mutants affecting resistance to the immunosuppressive drug, mycophenolic acid. J Biol Chem 277(30):27036-44 PMID:12016207
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549
- Higgins VJ, et al. (2002) Phenotypic analysis of gene deletant strains for sensitivity to oxidative stress. Yeast 19(3):203-14 PMID:11816028
- Jorgensen P, et al. (2002) Systematic identification of pathways that couple cell growth and division in yeast. Science 297(5580):395-400 PMID:12089449
- Rieger KJ, et al. (1999) Chemotyping of yeast mutants using robotics. Yeast 15(10B):973-86 PMID:10407277