Phenotype Help

SAG1 / YJR004C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

22 entries for 18 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
actin cytoskeleton morphology: abnormal
classical genetics null
Allele: sag1-Δ
S288CDetails: Delocalized actin patches, suggesting perturbation of actin polarization and polarized bud growth
Ghanegolmohammadi F, et al. (2021) PMID:34575807
bud morphology: decreased
classical genetics null
Allele: sag1-Δ
S288CDetails: Smaller bud size at M phase
Ghanegolmohammadi F, et al. (2021) PMID:34575807
cell size: decreased
classical genetics null
Allele: sag1-Δ
S288CDetails: Smaller cell size at G1
Ghanegolmohammadi F, et al. (2021) PMID:34575807
chemical compound accumulation: decreased
systematic mutation setnull
Allele: sag1-Δ
S288C protonMedia: external pH 5.0
Orij R, et al. (2012) PMID:23021432
chronological lifespan: decreased
systematic mutation setnull
Allele: sag1-Δ
S288CMarek A and Korona R (2013) PMID:24151994
haploproficient
heterozygous diploid, competitive growth

genome-wide fitness profiling

null
Allele: sag1-Δ
S288CMedia: turbidostat growth in FPM medium
Details: Relative growth score: 0.004
Pir P, et al. (2012) PMID:22244311
lipid particle morphology: abnormal
systematic mutation setnull
Allele: sag1-Δ
S288CDetails: reduced numbers of lipid droplets per cell
Ruggles KV, et al. (2014) PMID:24273168
mating response: abnormal
classical geneticsnull
Allele: sag1-Δ
W303Details: MATalpha cells fail to agglutinate in response to 'a' mating pheromone
Lipke PN, et al. (1989) PMID:2677666
mating response: absent
homozygous diploidunspecifiedOtherDetails: fails to agglutinate in response to 'a' mating pheromone; strain is homozygous MATalpha
Suzuki K and Yanagishima N (1986) PMID:3327603
mating response: decreased
heterozygous diploidunspecifiedOtherDetails: agglutinates less than wild type in response to 'a' mating pheromone; strain is homozygous MATalpha
Suzuki K and Yanagishima N (1986) PMID:3327603
Showing 1 to 10 of 22 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


Resources