Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.
14 entries for 9 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|
| budding pattern: abnormal | classical genetics | null Allele: pmt4-Δ | Other | Details: haploid daughter cells exhibit a bipolar budding pattern for the first bud, and thereafter exhibit normal axial budding | Sanders SL, et al. (1999) PMID:10366591 | |
| protein/peptide accumulation: decreased Reporter: pdr5-26 pdr5-C1427Y, an ERAD substrate | classical genetics | null Allele: pmt4-Δ | SEY6210 | Details: degradation enhanced | Arroyo J, et al. (2011) PMID:21231968 | |
| protein/peptide distribution: abnormal Reporter: Axl2p | classical genetics | null Allele: pmt4-Δ | Other | Sanders SL, et al. (1999) PMID:10366591 | ||
| protein/peptide distribution: absent Reporter: Fus1p | classical genetics | null Allele: pmt4-Δ | SEY6210 | Details: Fus1p accumulates intracellularly rather than in the plasma membrane | Proszynski TJ, et al. (2004) PMID:14742720 | |
| protein/peptide modification: absent Reporter: Fus1p | classical genetics | null Allele: pmt4-Δ | SEY6210 | Details: Fus1p is not glycosylated | Proszynski TJ, et al. (2004) PMID:14742720 | |
| protein/peptide modification: decreased Reporter: Axl2p | classical genetics | null Allele: pmt4-Δ | Other | Details: Axl2p is under-glycosylated | Sanders SL, et al. (1999) PMID:10366591 | |
| protein/peptide modification: decreased Reporter: Cts1p | classical genetics | null Allele: pmt4-Δ | SEY6210 | Details: Cts1p is under-glycosylated; mutant has no obvious growth phenotype | Immervoll T, et al. (1995) PMID:8585318 | |
| protein/peptide modification: decreased Reporter: Ncw2p | classical genetics | null Allele: pmt4-Δ | S288C | Details: decreased O-mannosylation of Ncw2p | Queiroz MG, et al. (2021) PMID:33945065 | |
| protein/peptide modification: decreased Reporter: Ncw2p | classical genetics | null Allele: pmt4-Δ | S288C | 0.0005% polyhexamethylene biguanide | Details: decrease in the O-mannosylation of Ncw2p that is stimulated in wt cells by polyhexamethylene biguanide treatment | Queiroz MG, et al. (2021) PMID:33945065 |
| resistance to chemicals: decreased | classical genetics | null Allele: pmt4-Δ | SEY6210 | rhodanine 3-acetic acid derivative | Arroyo J, et al. (2011) PMID:21231968 |
This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).
Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.
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