Interaction Help

ISA1 / YLL027W Interactions

Interaction annotations are curated by BioGRID and include physical or genetic interactions observed between at least two genes. An interaction annotation is composed of the interaction type, name of the interactor, assay type (e.g., Two-Hybrid), annotation type (e.g., manual or high-throughput), and a reference. Experimental details, phenotype, modification, and multiple mutant information are included when available.


Source: All physical and genetic interaction annotations listed in SGD are curated by BioGRID.

Genetic Interactions

An interaction is defined as an experimentally observed physical or genetic interaction between two genes. There may be more than one row listed for the same interactor if the interaction between it and the given gene was observed in separate studies. All interactions listed in SGD are curated by BioGRID.


Genetic Interactions

Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details about experiment type and any other genes involved in the interaction.

Interactor Interactor Allele Assay Annotation Action Phenotype SGA score P-value Source Reference

Physical Interactions

An interaction is defined as an experimentally observed physical or genetic interaction between two genes. There may be more than one row listed for the same interactor if the interaction between it and the given gene was observed in separate studies. All interactions listed in SGD are curated by BioGRID.


Physical Interactions 24 entries for 22 genes

Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details about experiment type and any other genes involved in the interaction.

InteractorAssayAnnotationActionModificationReference
CCR4Affinity Capture-RNAhigh-throughputHitNo ModificationMiller JE, et al. (2018) PMID:29158339

Intreaction in the presence of RanGTP|Low Abundant Cargo

CRM1Affinity Capture-MShigh-throughputHitNo ModificationKırlı K, et al. (2015) PMID:26673895
DHH1Affinity Capture-RNAhigh-throughputHitNo ModificationMiller JE, et al. (2018) PMID:29158339
EST1Affinity Capture-MShigh-throughputHitNo ModificationLin KW, et al. (2015) PMID:26365526
GIS2Affinity Capture-MShigh-throughputHitNo ModificationSammons MA, et al. (2011) PMID:21277287
HEK2Affinity Capture-RNAhigh-throughputHitNo ModificationHasegawa Y, et al. (2008) PMID:18805955
IBA57Affinity Capture-Westernmanually curatedHitNo ModificationGelling C, et al. (2008) PMID:18086897
IBA57Affinity Capture-Westernmanually curatedBaitNo ModificationGelling C, et al. (2008) PMID:18086897

BioID|Proximal mitochondrial proteins were detected using BioID analyses and proteins with a log2fold change >= 1.5 and a p-value =< 0.05 were considered significant.

MRPL28Proximity Label-MShigh-throughputHitNo ModificationSingh AP, et al. (2020) PMID:32877643

High Throughput: The experiment involved high-throughput sequencing of the RNAs that co-precipitated with TAP-tagged Nab2 (Nab2-TAP).

NAB2Affinity Capture-RNAhigh-throughputHitNo ModificationBatisse J, et al. (2009) PMID:19840948
Showing 1 to 10 of 24 entries

Interaction Network

This diagram displays physical (purple lines) and genetic (green lines) interactions between the given gene (yellow circle) and its interactors (gray circles) based on the number of experiments supporting each interaction (adjustable using the slider at the bottom). Interactions between the interactors for a given gene are also shown.


Reset

Click on a gene to go to its specific page within SGD; drag any of the gene objects around within the visualization for easier viewing; filter by interaction type (genetic or physical) using the radio buttons; click “Reset” to automatically redraw the diagram; filter the number of interactors displayed by adjusting the number of experiments supporting a gene's interaction with the given gene by clicking anywhere on the slider bar or dragging the tab to the desired filter number.

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Resources


BioGRID | CYC2008 | DIP | GeneMANIA | IMP | InterologFinder | ModelArchive | TheCellMap

IBA57