AEP1 / YMR064W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; in systematic studies, null mutant is incapable of respiratory growth and grows slowly under standard fermentative growth conditions; also shows sensitivity to lipids, lower resistance to ethanol, abnormal mitochondrial morphology and decreased mitophagy; homozygous null mutation in diploids causes sensitivity to oxidative stress, but increases innate thermotolerance and resistance to benomyl, actinomycin D, Calcofluor White, idarubicin and tirapazamine

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources