Phenotype Help

YNL040W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

17 entries for 7 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
chemical compound accumulation: increased
systematic mutation setnull
Allele: ynl040w-Δ
S288C cadmium cationYu D, et al. (2012) PMID:23151179
chemical compound accumulation: increased
systematic mutation setnull
Allele: ynl040w-Δ
S288C molybdenum cationYu D, et al. (2012) PMID:23151179
competitive fitness: decreased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: ynl040w-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 0.972
Breslow DK, et al. (2008) PMID:18622397
resistance to chemicals: decreased
systematic mutation set null
Allele: ynl040w-Δ
S288C12 mM sodium disulfiteJin X, et al. (2021) PMID:34944020
resistance to chemicals: decreased
classical geneticsnull
Allele: ynl040w-Δ
S288C45 ng/ml cycloheximideSamanfar B, et al. (2014) PMID:24535059
resistance to chemicals: decreased
classical geneticsnull
Allele: ynl040w-Δ
S288C18 mg/ml paromomycinSamanfar B, et al. (2014) PMID:24535059
resistance to chemicals: decreased
classical genetics null
Allele: ynl040w-Δ
S288C0.3 μg/ml cycloheximideDetails: decreased resistance to cycloheximide, an inhibitor of translation elongation; overexpression of AlaRS (ALA1) or ThrRS (THS1) ameliorates sensitivity of the null mutant
Li ZH and Zhou XL (2024) PMID:38869066
resistance to chemicals: increased
systematic mutation setnull
Allele: ynl040w-Δ
S288C wortmanninXie MW, et al. (2005) PMID:15883373
resistance to chemicals: increased
systematic mutation setnull
Allele: ynl040w-Δ
S288C sirolimusDetails: sirolimus is rapamycin
Xie MW, et al. (2005) PMID:15883373
resistance to chemicals: increased
systematic mutation setnull
Allele: ynl040w-Δ
S288C250 ug/ml; synthetic cyclic depsipeptide related to natural kahalalides elisidepsinHerrero AB, et al. (2008) PMID:19047157
Showing 1 to 10 of 17 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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