ARP5 / YNL059C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene in S288C, but essential in sigma1278b; S288C-derived null mutant has a large cell size and abnormally elongated buds; null mutant is heat sensitive, has a decreased growth rate on rich media and decreased competitive fitness on various media; null mutant is sensitive to oxidative stress, acid and alkaline pH, zinc and cadmium treatment, enzymatic treatment with zymolyase, and treatment with zymocin or killer toxin; null mutant has an altered ionome and a decreased ability to accumulate polyphosphate and glycogen; null has a decreased chronological lifespan, and decreased innate thermotolerance; overexpression results in enhanced invasive growth

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources