GCD10 / YNL062C Homology
- Standard Name
- GCD10 1
- Systematic Name
- YNL062C
- SGD ID
- SGD:S000005006
- Aliases
- TRM6 5
- Feature Type
- ORF , Verified
- Description
- Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p; required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression 2 3
- Name Description
- General Control Derepressed 4
- Comparative Info
-
Homologs
Homology calls are sourced from the Alliance of Genome Resources. Many aspects of data integration presented at the Alliance require a common set of orthology relationships among genes for the organisms represented, including human. The Alliance provides the results of all methods that have been benchmarked by the Quest for Orthologs Consortium (QfO). The homolog inferences from the different methods have been integrated using the DRSC Integrative Ortholog Prediction Tool (DIOPT), which integrates a number of existing methods including those used by the Alliance: Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, and ZFIN.
7 entries for 7 homologsIncrease the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.
| Species | Gene ID | Gene name | Source |
|---|---|---|---|
| Caenorhabditis elegans | WB:WBGene00014120 | trmt-6 | Alliance |
| Danio rerio | ZFIN:ZDB-GENE-051120-141 | trmt6 | Alliance |
| Drosophila melanogaster | FB:FBgn0031832 | Trmt6 | Alliance |
| Homo sapiens | HGNC:20900 | TRMT6 | Alliance |
| Mus musculus | MGI:1914176 | Trmt6 | Alliance |
| Rattus norvegicus | RGD:1308877 | Trmt6 | Alliance |
| Xenopus tropicalis | Xenbase:XB-GENE-973293 | trmt6 | Alliance |
Functional Complementation
Information about cross-species functional complementation between yeast and other species, curated by SGD and the Princeton Protein Orthology Database (P-POD).
1 entry for 1 complementIncrease the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.
| Species | Gene ID | Strain background | Direction | Details | Source | Reference |
|---|---|---|---|---|---|---|
| Homo sapiens | HGNC:20900 | S288C | other complements yeast | Co-expression of human TRMT6 and TRMT61A functionally complement the heat sensitivity of the S. cerevisiae gcd10-(trm6-504) mutant. Expression of human TRMT6 alone does not complement. | SGD | Ozanick S, et al. (2005) PMID:16043508 |
Fungal Homologs
Fungal Homology calls are sourced from AllianceMine, which compiles fungal homology calls from FungiDB, CGD, Panther, PomBase, TreeFam, HomoloGene, and SGD.
17 entries for 17 homologsIncrease the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.
| Species | Gene ID | Gene name | Description | Source |
|---|---|---|---|---|
| A. flavus NRRL3357 | AFLA_024940 | FungiDB | ||
| A. niger ATCC 1015 | ASPNIDRAFT_183782 | FungiDB | ||
| C. gattii WM276 | CGB_C2700C | FungiDB | ||
| C. immitis H538.4 | CIHG_00774 | FungiDB | ||
| C. immitis RS | CIMG_06388 | FungiDB | ||
| C. neoformans var. grubii H99 | CNAG_01676 | FungiDB | ||
| C. neoformans var. neoformans JEC21 | CNC01870 | FungiDB | ||
| C. posadasii C735 delta SOWgp | CPC735_028940 | FungiDB | ||
| N. crassa OR74A | NCU09571 | FungiDB | ||
| S. pombe | SPBC800.08 | PomBase |
External Identifiers
List of external identifiers for the protein from various database sources.
23 entries for 10 sourcesIncrease the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.
Resources
Homologs
AGD | AnalogYeast | AspGD | BLASTP at NCBI | CGD | FungiDB | PhylomeDB | PomBase | YGOB | YOGY
Protein Databases
AlphaFold Protein Structure | GPMDB | ModelArchive | Pfam domains | SUPERFAMILY | TopologYeast | UniProtKB
Localization
CYCLoPs | dHITS | LoQAtE | YeastGFP | YeastRC Public Images | YeastRGB | YPL+
Post-translational Modifications
CoSMoS.c. | PhosphoGRID | PhosphoPep
S288C only
BLASTN | BLASTP | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species
BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi