Regulation Help

NIS1 / YNL078W Regulation

Transcriptional regulation information for a gene, including any predicted DNA binding site motifs (YeTFaSCo) for the gene's protein product, as well as any of its targets (genes it regulates) or regulators (genes that regulate it), based on experimental evidence. For genes with regulatory targets, shared GO Biological Process terms for these targets are listed.


    Domains and Classification

    Collection of domains associated with the protein based on various sources, including the protein coordinates for the domain, a domain Description, a Source and corresponding accession ID, and the number of S. cerevisiae genes that share the same domain.


    Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

    Gene Protein Coordinates Accession ID Description Source No. of Genes with Domain

    Targets

    This table lists putative transcriptional regulatory targets for the central gene represented on this page. These targets were identified based on the presence of predicted regulator binding sites or experimental regulator binding in the target promoter, and/or changes in the target gene’s transcript levels in regulator mutant strains. Data includes high-throughput techniques such as microarray, RNA-seq, and ChIP assays; information about the experiment and assay type, constructs, conditions, and strains, as well as a reference, are provided for each Regulator annotation.


    Manually Curated

    Increase the total number of rows displayed on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; to filter the table by a specific experiment type, type a keyword into the Filter box (for example, “microarray”); download this table as a .txt file using the Download button or click Analyze to further view and analyze the list of target genes using GO Term Finder, GO Slim Mapper, or SPELL.

    Target Direction Regulation of Happens During Evidence Strain Background Reference

     

    High-throughput

    Increase the total number of rows displayed on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; to filter the table by a specific experiment type, type a keyword into the Filter box (for example, “microarray”); download this table as a .txt file using the Download button or click Analyze to further view and analyze the list of target genes using GO Term Finder, GO Slim Mapper, or SPELL.

    Target Direction Regulation of Happens During Evidence Strain Background Reference

    Increase the total number of rows displayed on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; to filter the table by a specific experiment type, type a keyword into the Filter box (for example, “microarray”); download this table as a .txt file using the Download button or click Analyze to further view and analyze the list of target genes using GO Term Finder, GO Slim Mapper, or SPELL.

    Target Direction Regulation of Happens During Evidence Strain Background Reference

    Shared GO Processes Among Targets

    The shared GO processes listed in this table are based on the data presented in the Targets section above; shared GO terms, the number of target genes that share them, and the P-value are all indicated in the table.


    Increase the total number of rows displayed on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; download this table as a .txt file using the Download button; after filtering the above table, the option to ”Recalculate With New Filter” will appear next to the Download button in this Shared GO Processes table.

    GO Term ID GO Term Number of genes P-Value

    Regulators

    This table lists genes that are putative regulators of the central gene represented on this page, based primarily on experiments showing that a regulator binds to the gene’s promoter or affects the gene’s transcription when the regulator is mutated. This includes data generated by high-throughput techniques such as microarray, RNA-seq, and ChIP assays; information about the experiment and assay type, constructs, conditions, and strains, as well as a reference, are provided for each Regulator annotation.


    Manually Curated

    Increase the total number of rows displayed on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; to filter the table by a specific experiment type, type a keyword into the Filter box (for example, “microarray”); download this table as a .txt file using the Download button or click Analyze to further view and analyze the list of target genes using GO Term Finder, GO Slim Mapper, or SPELL.

    Regulator Happens During Regulator Type Direction Regulation Of Happens During Evidence Strain Background Reference

     

    High-throughput

    Increase the total number of rows displayed on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; to filter the table by a specific experiment type, type a keyword into the Filter box (for example, “microarray”); download this table as a .txt file using the Download button or click Analyze to further view and analyze the list of target genes using GO Term Finder, GO Slim Mapper, or SPELL.

    Regulator Happens During Regulator Type Direction Regulation Of Happens During Evidence Strain Background Reference

    Increase the total number of rows displayed on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; to filter the table by a specific experiment type, type a keyword into the Filter box (for example, “microarray”); download this table as a .txt file using the Download button or click Analyze to further view and analyze the list of target genes using GO Term Finder, GO Slim Mapper, or SPELL.

    Regulator Happens During Regulator Type Direction Regulation Of Happens During Evidence Strain Background Reference

    Regulation Network

    This diagram displays targets (purple) and regulators (green) of the given gene (blue) based on the data presented in the Targets and Regulators tables and therefore includes high-throughput data generated by techniques such as microarray, RNA-seq, and ChIP assays. The arrows move in the direction of Regulator -> Target and include any regulatory relationships between genes other than the given gene.