Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.
34 entries for 15 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|
| autophagy: increased | classical genetics | null Allele: pho91-Δ | Other | Media: phosphate starvation Details: autophagy increased under phosphate starvation but not nitrogen starvation; autophagy measured by processing of a CFP-peptide reporter | Yokota H, et al. (2017) PMID:28013049 | |
| chemical compound accumulation: increased | classical genetics | null Allele: pho91-Δ | S288C | phosphatidylcholine | Details: level of phosphatidylcholine increased relative to wt cells | Subitha M, et al. (2020) PMID:32462239 |
| chemical compound accumulation: increased | classical genetics | null Allele: pho91-Δ | S288C | sterol ester | Details: 155-170% increase in the levels of sterol ester relative to wt | Subitha M, et al. (2020) PMID:32462239 |
| chemical compound accumulation: increased | classical genetics | null Allele: pho91-Δ | S288C | triglyceride | Details: 150-170% increase in the levels of triacylglycerol relative to wt | Subitha M, et al. (2020) PMID:32462239 |
| competitive fitness: decreased | competitive growth fitness profiling using complete deletion alleles | null Allele: pho91-Δ | S288C | Media: minimal medium Details: Relative fitness score: 0.987 | Breslow DK, et al. (2008) PMID:18622397 | |
| lipid particle morphology: abnormal | classical genetics | null Allele: pho91-Δ | S288C | Details: significant increased in the number of lipid droplets per cell | Subitha M, et al. (2020) PMID:32462239 | |
| metal resistance: decreased | classical genetics | null Allele: pho91-Δ | S288C | 0.02-0.04 mM cadmium(2+) | Details: decreased resistance to Cd2+ | Farofonova V, et al. (2023) PMID:36753030 |
| metal resistance: increased | classical genetics | null Allele: pho91-Δ | S288C | 1-3 mM manganese(2+) | Details: increased resistance to Mn2+ | Farofonova V, et al. (2023) PMID:36753030 |
| oxidative stress resistance: increased | classical genetics | null Allele: pho91-Δ | S288C | 1-1.5 mM hydrogen peroxide | Details: increased resistance to peroxide | Farofonova V, et al. (2023) PMID:36753030 |
| resistance to chemicals: decreased | systematic mutation set | null Allele: pho91-Δ | S288C | ciclopirox olamine | Sukhai MA, et al. (2013) PMID:23202731 |
This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).
Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.
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