Literature Help
PPG1 / YNR032W Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Niphadkar S, et al. (2024) The PP2A-like phosphatase Ppg1 mediates assembly of the Far complex to balance gluconeogenic outputs and enables adaptation to glucose depletion. PLoS Genet 20(3):e1011202 PMID:38452140
- Onishi M, et al. (2023) The GET pathway serves to activate Atg32-mediated mitophagy by ER targeting of the Ppg1-Far complex. Life Sci Alliance 6(4) PMID:36697253
- Furukawa K, et al. (2021) Mitophagy regulation mediated by the Far complex in yeast. Autophagy 17(4):1042-1043 PMID:33530805
- Kubota M and Okamoto K (2021) The protein N-terminal acetyltransferase A complex contributes to yeast mitophagy via promoting expression and phosphorylation of Atg32. J Biochem 170(2):175-182 PMID:34115119
- Innokentev A, et al. (2020) Association and dissociation between the mitochondrial Far complex and Atg32 regulate mitophagy. Elife 9 PMID:33317697
- Lv X, et al. (2019) Identification of gene products that control lipid droplet size in yeast using a high-throughput quantitative image analysis. Biochim Biophys Acta Mol Cell Biol Lipids 1864(2):113-127 PMID:30414449
- Furukawa K, et al. (2018) The PP2A-like Protein Phosphatase Ppg1 and the Far Complex Cooperatively Counteract CK2-Mediated Phosphorylation of Atg32 to Inhibit Mitophagy. Cell Rep 23(12):3579-3590 PMID:29925000
- Kim HS, et al. (2011) Identification of novel genes responsible for ethanol and/or thermotolerance by transposon mutagenesis in Saccharomyces cerevisiae. Appl Microbiol Biotechnol 91(4):1159-72 PMID:21556919
- Hirasaki M, et al. (2010) Deciphering cellular functions of protein phosphatases by comparison of gene expression profiles in Saccharomyces cerevisiae. J Biosci Bioeng 109(5):433-41 PMID:20347764
- Zhang W and Durocher D (2010) De novo telomere formation is suppressed by the Mec1-dependent inhibition of Cdc13 accumulation at DNA breaks. Genes Dev 24(5):502-15 PMID:20194442
- Posas F, et al. (1993) The gene PPG encodes a novel yeast protein phosphatase involved in glycogen accumulation. J Biol Chem 268(2):1349-54 PMID:7678255
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
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Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Kunchala P, et al. (2024) Plasticity of the mitotic spindle in response to karyotype variation. Curr Biol 34(15):3416-3428.e4 PMID:39043187
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Lyons SP, et al. (2018) A Quantitative Chemical Proteomic Strategy for Profiling Phosphoprotein Phosphatases from Yeast to Humans. Mol Cell Proteomics 17(12):2448-2461 PMID:30228194
- Garipler G, et al. (2014) Deletion of conserved protein phosphatases reverses defects associated with mitochondrial DNA damage in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 111(4):1473-8 PMID:24474773
- Castermans D, et al. (2012) Glucose-induced posttranslational activation of protein phosphatases PP2A and PP1 in yeast. Cell Res 22(6):1058-77 PMID:22290422
- Kim HS, et al. (2012) Insertion of transposon in the vicinity of SSK2 confers enhanced tolerance to furfural in Saccharomyces cerevisiae. Appl Microbiol Biotechnol 95(2):531-40 PMID:22639140
- Liu C, et al. (2009) A genome-wide synthetic dosage lethality screen reveals multiple pathways that require the functioning of ubiquitin-binding proteins Rad23 and Dsk2. BMC Biol 7:75 PMID:19909498
- Bishop AL, et al. (2007) Phenotypic heterogeneity can enhance rare-cell survival in 'stress-sensitive' yeast populations. Mol Microbiol 63(2):507-20 PMID:17176259
- Butcher RA, et al. (2006) Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway. Nat Chem Biol 2(2):103-9 PMID:16415861
- Titz B, et al. (2006) Transcriptional activators in yeast. Nucleic Acids Res 34(3):955-67 PMID:16464826
- Gerik KJ, et al. (2005) Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans. Mol Microbiol 58(2):393-408 PMID:16194228
- Van Hoof C, et al. (2005) Specific interactions of PP2A and PP2A-like phosphatases with the yeast PTPA homologues, Ypa1 and Ypa2. Biochem J 386(Pt 1):93-102 PMID:15447631
- Tong AH, et al. (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13 PMID:14764870
- Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 PMID:14562095
- Wang H, et al. (2003) Interaction with Tap42 is required for the essential function of Sit4 and type 2A phosphatases. Mol Biol Cell 14(11):4342-51 PMID:14551259
- Sakumoto N, et al. (2002) A series of double disruptants for protein phosphatase genes in Saccharomyces cerevisiae and their phenotypic analysis. Yeast 19(7):587-99 PMID:11967829
Reviews
No reviews curated.
Download References (.nbib)
- Maruyama T, et al. (2024) Mechanisms of mitochondrial reorganization. J Biochem 175(2):167-178 PMID:38016932
- Abeliovich H (2023) Mitophagy in yeast: known unknowns and unknown unknowns. Biochem J 480(20):1639-1657 PMID:37850532
- Shen ZF, et al. (2023) Current opinions on mitophagy in fungi. Autophagy 19(3):747-757 PMID:35793406
- Schuster R and Okamoto K (2022) An overview of the molecular mechanisms of mitophagy in yeast. Biochim Biophys Acta Gen Subj 1866(11):130203 PMID:35842014
- Innokentev A and Kanki T (2021) Mitophagy in Yeast: Molecular Mechanism and Regulation. Cells 10(12) PMID:34944077
- Liu Y and Okamoto K (2021) Regulatory mechanisms of mitophagy in yeast. Biochim Biophys Acta Gen Subj 1865(5):129858 PMID:33545228
- Onishi M, et al. (2021) Molecular mechanisms and physiological functions of mitophagy. EMBO J 40(3):e104705 PMID:33438778
- Ariño J, et al. (2019) Ser/Thr protein phosphatases in fungi: structure, regulation and function. Microb Cell 6(5):217-256 PMID:31114794
- Furukawa K, et al. (2019) Regulatory Mechanisms of Mitochondrial Autophagy: Lessons From Yeast. Front Plant Sci 10:1479 PMID:31803214
- Kirkin V and Rogov VV (2019) A Diversity of Selective Autophagy Receptors Determines the Specificity of the Autophagy Pathway. Mol Cell 76(2):268-285 PMID:31585693
- Offley SR and Schmidt MC (2019) Protein phosphatases of Saccharomyces cerevisiae. Curr Genet 65(1):41-55 PMID:30225534
- Deprez MA, et al. (2018) The TORC1-Sch9 pathway as a crucial mediator of chronological lifespan in the yeast Saccharomyces cerevisiae. FEMS Yeast Res 18(5) PMID:29788208
- Furukawa K and Kanki T (2018) PP2A-like protein phosphatase Ppg1: an emerging negative regulator of mitophagy in yeast. Autophagy 14(12):2171-2172 PMID:30145928
- Zhang W, et al. (2018) Regulation of Sensing, Transportation, and Catabolism of Nitrogen Sources in Saccharomyces cerevisiae. Microbiol Mol Biol Rev 82(1) PMID:29436478
- Conrad M, et al. (2014) Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae. FEMS Microbiol Rev 38(2):254-99 PMID:24483210
- Ariño J (2002) Novel protein phosphatases in yeast. Eur J Biochem 269(4):1072-7 PMID:11856338
- Zabrocki P, et al. (2002) Protein phosphatase 2A on track for nutrient-induced signalling in yeast. Mol Microbiol 43(4):835-42 PMID:11929536
- Stark MJ (1996) Yeast protein serine/threonine phosphatases: multiple roles and diverse regulation. Yeast 12(16):1647-75 PMID:9123967
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Download References (.nbib)
- Hirasaki M, et al. (2010) Deciphering cellular functions of protein phosphatases by comparison of gene expression profiles in Saccharomyces cerevisiae. J Biosci Bioeng 109(5):433-41 PMID:20347764
- Posas F, et al. (1993) The gene PPG encodes a novel yeast protein phosphatase involved in glycogen accumulation. J Biol Chem 268(2):1349-54 PMID:7678255
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- Niphadkar S, et al. (2024) The PP2A-like phosphatase Ppg1 mediates assembly of the Far complex to balance gluconeogenic outputs and enables adaptation to glucose depletion. PLoS Genet 20(3):e1011202 PMID:38452140
- Tian Y and Okamoto K (2024) The nascent polypeptide-associated complex subunit Egd1 is required for efficient selective mitochondrial degradation in budding yeast. Sci Rep 14(1):546 PMID:38177147
- Caydasi AK, et al. (2023) SWR1 chromatin remodeling complex prevents mitotic slippage during spindle position checkpoint arrest. Mol Biol Cell 34(2):ar11 PMID:36542480
- Michaelis AC, et al. (2023) The social and structural architecture of the yeast protein interactome. Nature 624(7990):192-200 PMID:37968396
- Onishi M, et al. (2023) The GET pathway serves to activate Atg32-mediated mitophagy by ER targeting of the Ppg1-Far complex. Life Sci Alliance 6(4) PMID:36697253
- Lu PYT, et al. (2022) A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans. Genetics 222(3) PMID:36066422
- Innokentev A, et al. (2020) Association and dissociation between the mitochondrial Far complex and Atg32 regulate mitophagy. Elife 9 PMID:33317697
- van Leeuwen J, et al. (2020) Systematic analysis of bypass suppression of essential genes. Mol Syst Biol 16(9):e9828 PMID:32939983
- Furukawa K, et al. (2018) The PP2A-like Protein Phosphatase Ppg1 and the Far Complex Cooperatively Counteract CK2-Mediated Phosphorylation of Atg32 to Inhibit Mitophagy. Cell Rep 23(12):3579-3590 PMID:29925000
- Kuzmin E, et al. (2018) Systematic analysis of complex genetic interactions. Science 360(6386) PMID:29674565
- Miller JE, et al. (2018) Genome-Wide Mapping of Decay Factor-mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4. G3 (Bethesda) 8(1):315-330 PMID:29158339
- Shulist K, et al. (2017) Interrogation of γ-tubulin alleles using high-resolution fitness measurements reveals a distinct cytoplasmic function in spindle alignment. Sci Rep 7(1):11398 PMID:28900268
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Lahiri S, et al. (2014) A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria. PLoS Biol 12(10):e1001969 PMID:25313861
- Aristizabal MJ, et al. (2013) High-throughput genetic and gene expression analysis of the RNAPII-CTD reveals unexpected connections to SRB10/CDK8. PLoS Genet 9(8):e1003758 PMID:24009531
- Surma MA, et al. (2013) A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress. Mol Cell 51(4):519-30 PMID:23891562
- Willmund F, et al. (2013) The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell 152(1-2):196-209 PMID:23332755
- Kaluarachchi Duffy S, et al. (2012) Exploring the yeast acetylome using functional genomics. Cell 149(4):936-48 PMID:22579291
- Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801 PMID:22282571
- Bandyopadhyay S, et al. (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9 PMID:21127252
- Breitkreutz A, et al. (2010) A global protein kinase and phosphatase interaction network in yeast. Science 328(5981):1043-6 PMID:20489023
- Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31 PMID:20093466
- Liu B, et al. (2010) The polarisome is required for segregation and retrograde transport of protein aggregates. Cell 140(2):257-67 PMID:20141839
- Zhang W and Durocher D (2010) De novo telomere formation is suppressed by the Mec1-dependent inhibition of Cdc13 accumulation at DNA breaks. Genes Dev 24(5):502-15 PMID:20194442
- Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63 PMID:19269370
- Liu C, et al. (2009) A genome-wide synthetic dosage lethality screen reveals multiple pathways that require the functioning of ubiquitin-binding proteins Rad23 and Dsk2. BMC Biol 7:75 PMID:19909498
- Tong AH, et al. (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13 PMID:14764870
- Wang H, et al. (2003) Interaction with Tap42 is required for the essential function of Sit4 and type 2A phosphatases. Mol Biol Cell 14(11):4342-51 PMID:14551259
- Ito T, et al. (2001) A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc Natl Acad Sci U S A 98(8):4569-74 PMID:11283351
- Uetz P, et al. (2000) A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403(6770):623-7 PMID:10688190
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- St John N, et al. (2020) Genome Profiling for Aflatoxin B1 Resistance in Saccharomyces cerevisiae Reveals a Role for the CSM2/SHU Complex in Tolerance of Aflatoxin B1-Associated DNA Damage. G3 (Bethesda) 10(11):3929-3947 PMID:32994210
- Fröhlich F, et al. (2015) The GARP complex is required for cellular sphingolipid homeostasis. Elife 4 PMID:26357016
- Gaupel AC, et al. (2014) High throughput screening identifies modulators of histone deacetylase inhibitors. BMC Genomics 15(1):528 PMID:24968945
- Marek A and Korona R (2013) Restricted pleiotropy facilitates mutational erosion of major life-history traits. Evolution 67(11):3077-86 PMID:24151994
- Shively CA, et al. (2013) Genetic networks inducing invasive growth in Saccharomyces cerevisiae identified through systematic genome-wide overexpression. Genetics 193(4):1297-310 PMID:23410832
- Qian W, et al. (2012) The genomic landscape and evolutionary resolution of antagonistic pleiotropy in yeast. Cell Rep 2(5):1399-410 PMID:23103169
- Jayakody LN, et al. (2011) Identification of glycolaldehyde as the key inhibitor of bioethanol fermentation by yeast and genome-wide analysis of its toxicity. Biotechnol Lett 33(2):285-92 PMID:20960220
- Venters BJ, et al. (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92 PMID:21329885
- Alamgir M, et al. (2010) Chemical-genetic profile analysis of five inhibitory compounds in yeast. BMC Chem Biol 10:6 PMID:20691087
- Zhou X, et al. (2009) A genome-wide screen in Saccharomyces cerevisiae reveals pathways affected by arsenic toxicity. Genomics 94(5):294-307 PMID:19631266
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Cipollina C, et al. (2008) Saccharomyces cerevisiae SFP1: at the crossroads of central metabolism and ribosome biogenesis. Microbiology (Reading) 154(Pt 6):1686-1699 PMID:18524923
- Bishop AL, et al. (2007) Phenotypic heterogeneity can enhance rare-cell survival in 'stress-sensitive' yeast populations. Mol Microbiol 63(2):507-20 PMID:17176259
- Butcher RA, et al. (2006) Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway. Nat Chem Biol 2(2):103-9 PMID:16415861
- Kawahata M, et al. (2006) Yeast genes involved in response to lactic acid and acetic acid: acidic conditions caused by the organic acids in Saccharomyces cerevisiae cultures induce expression of intracellular metal metabolism genes regulated by Aft1p. FEMS Yeast Res 6(6):924-36 PMID:16911514
- Sopko R, et al. (2006) Mapping pathways and phenotypes by systematic gene overexpression. Mol Cell 21(3):319-30 PMID:16455487
- Mollapour M, et al. (2004) Screening the yeast deletant mutant collection for hypersensitivity and hyper-resistance to sorbate, a weak organic acid food preservative. Yeast 21(11):927-46 PMID:15334557
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549