POP2 / YNR052C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

POP2/YNL052C is a non-essential gene; null mutants are viable but exhibit a range of phenotypic changes including increased chemical compound accumulation, abnormal chromosome and plasmid maintenance, increased cold sensitivity, decreased filamentous growth, decreased metal resistance, altered RNA accumulation, decreased toxin resistance, decreased vegetative growth, decreased acid pH resistance, decreased anaerobic growth, abnormal budding pattern, abnormal cell shape, increased cell size, decreased chronological lifespan, abnormal colony appearance, decreased competitive fitness, decreased endocytosis, decreased fermentative growth rate, increased heat sensitivity, decreased hydrostatic pressure resistance, increased killer toxin resistance, decreased mitotic recombination, decreased oxidative stress resistance, absent respiratory growth, decreased sporulation efficiency, decreased stress resistance, decreased transposable element transposition, decreased utilization rates of carbon and nitrogen sources, decreased UV resistance, and abnormal vacuolar morphology. Overexpression of POP2 results in increased invasive growth.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources