STE4 / YOR212W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; conditional mutant is alpha-factor resistant, being unable to undergo pheromone-induced cell cycle arrest, unable to form shmoos, unable to produce mating pheromone and is sterile; overexpression results in a decreased growth rate and the accumulation of large, misshapen, unbudded cells in G1 and S phase; overexpression results in activation of Fus3p and Kss1p in the absence of pheromone; mutation of a monoubiquitination site results in cells that initiate polarized growth in response pheromone stimulation more rapidly than wt

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources