ALD4 / YOR374W Homology


Standard Name
ALD4 1
Systematic Name
YOR374W
SGD ID
SGD:S000005901
Aliases
ALDH2 12 , ALD7 15
Feature Type
ORF , Verified
Description
Mitochondrial aldehyde dehydrogenase; K+ dependent enzyme that can use either NADP+ or NAD+ as cofactor; required for growth on ethanol and for conversion of acetaldehyde to acetate; can substitute for cytosolic NADP-dependent aldehyde dehydrogenase when directed to the cytosol; influences lipid metabolism; polymerizes into filaments in meiotic cells; phosphorylated; expression is glucose repressed; human homolog ALDH2 can complement a yeast ald4 mutant 1 2 3 4 5 6
Name Description
ALdehyde Dehydrogenase 1
Comparative Info

Homologs

Homology calls are sourced from the Alliance of Genome Resources. Many aspects of data integration presented at the Alliance require a common set of orthology relationships among genes for the organisms represented, including human. The Alliance provides the results of all methods that have been benchmarked by the Quest for Orthologs Consortium (QfO). The homolog inferences from the different methods have been integrated using the DRSC Integrative Ortholog Prediction Tool (DIOPT), which integrates a number of existing methods including those used by the Alliance: Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, and ZFIN.


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Species Gene ID Gene name Source

Functional Complementation

Information about cross-species functional complementation between yeast and other species, curated by SGD and the Princeton Protein Orthology Database (P-POD).


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Gene Species Gene ID Strain background Direction Details Source Reference

Fungal Homologs

Fungal Homology calls are sourced from AllianceMine, which compiles fungal homology calls from FungiDB, CGD, Panther, PomBase, TreeFam, HomoloGene, and SGD.


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Species Gene ID Gene name Description Source

External Identifiers

List of external identifiers for the protein from various database sources.


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External ID Source

Resources