SSN3 / YPL042C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

SSN3/YPL042C is a non-essential gene in reference strain S288C; null mutants are viable but display broad defects including decreased vegetative and respiratory growth and reduced competitive fitness. Cellular morphology and processes are altered, including abnormal vacuolar and lipid particle morphology, increased chitin deposition, enlarged cell size, and decreased endocytosis. Stress tolerance is compromised, with decreased resistance to UV, heat, desiccation, acidic pH, starvation, and metals. Developmental output is reduced, with lower sporulation efficiency. Genome-associated readouts include decreased transposable element transposition and increased telomere length.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources