CQD1 / YPL109C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; null mutant shows altered distribution of coenzyme Q, decreased respiratory growth, decreased prion formation, and decreased competitive fitness in ethanol and on glycerol and minimal media, but increased fitness on rich medium; null mutant shows decreased resistance to the DNA-damaging agent MMS and the histone deacetylase inhibitor CG-1521; heterozygous diploid is haploproficient and shows decreased resistance to the immunosuppressant ascomycin; overexpression causes decreased vegetative growth but increased invasive growth on nitrogen-sufficient medium

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources