COX11 / YPL132W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; null mutant is incapable of respiratory growth on nonfermentable carbon sources and grows slowly on fermentable carbon sources (petite phenotype); null mutant is also highly sensitive to oxidative stress caused by hydrogen peroxide and shows increased frequency of nonfunctional mitochondrial genome (rho- mutations); mutation within the copper binding site has no effect on oxidative stress resistance but still blocks respiratory growth; in systematic studies mutants exhibit reduced ability to form biofilms and show elevated chitin deposition

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources