IMT4 / YNCE0006W Overview
- Standard Name
- IMT4 1
- Systematic Name
- YNCE0006W
- SGD ID
- SGD:S000006660
- Aliases
- tM(CAU)E , tRNA-Met
- Feature Type
- tRNA gene
- Description
- Methionine initiator tRNA (tRNA-Met); predicted by tRNAscan-SE analysis; one of four initiator methionine tRNAs in yeast that are functional for translation 1 2
- Name Description
- Initiator Methionine tRNA 1
- RNAcentral ID
- URS00005350CD
- Secondary Structure
-
- Comparative Info
-
Sequence
The S. cerevisiae Reference Genome sequence is derived from laboratory strain S288C. Download DNA or protein sequence, view genomic context and coordinates. Click "Sequence Details" to view all sequence information for this locus, including that for other strains.
Analyze Sequence
S288C only
BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes
S288C vs. other species
Alleles
Curated mutant alleles for the specified gene, listed alphabetically. Click on the allele name to open the allele page. Click "SGD search" to view all alleles in search results.
View all IMT4 alleles in SGD search
Gene Ontology
GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code. SGD has manually curated and high-throughput GO Annotations, both derived from the literature, as well as computational, or predicted, annotations. Click "Gene Ontology Details" to view all GO information and evidence for this locus as well as biological processes it shares with other genes.
View computational annotations
Molecular Function
- Manually Curated
- enables eukaryotic initiation factor eIF2 binding (IDA)
- enables triplet codon-amino acid adaptor activity (ISM)
Biological Process
- Manually Curated
- involved in translational initiation (IC)
Cellular Component
- Manually Curated
- located in cytosol (IC)
- part of eukaryotic 43S preinitiation complex (IDA)
- part of eukaryotic 48S preinitiation complex (IDA)
Phenotype
Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided. Click "Phenotype Details" to view all phenotype annotations and evidence for this locus as well as phenotypes it shares with other genes.
Classical Genetics
- null
- overexpression
- null
Large-scale Survey
Interaction
Interaction annotations are curated by BioGRID and include physical or genetic interactions observed between at least two genes. An interaction annotation is composed of the interaction type, name of the interactor, assay type (e.g., Two-Hybrid), annotation type (e.g., manual or high-throughput), and a reference, as well as other experimental details. Click "Interaction Details" to view all interaction annotations and evidence for this locus, including an interaction visualization.
7 total interactions for 7 unique genes
Physical Interactions
- Affinity Capture-RNA: 2
Genetic Interactions
- Dosage Rescue: 1
- Phenotypic Suppression: 3
- Synthetic Rescue: 1
Regulation
The number of putative Regulators (genes that regulate it) and Targets (genes it regulates) for the given locus, based on experimental evidence. This evidence includes data generated through high-throughput techniques. Click "Regulation Details" to view all regulation annotations, shared GO enrichment among regulation Targets, and a regulator/target diagram for the locus.
- Regulators
- 2
- Targets
- 0
Literature
All manually curated literature for the specified gene, organized into topics according to their relevance to the gene (Primary Literature, Additional Literature, or Review). Click "Literature Details" to view all literature information for this locus, including shared literature between genes.