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YRF1-8 / YOR396W Protein

Protein abundance data, domains, shared domains with other proteins, protein sequence retrieval for various strains, sequence-based physico-chemical properties, protein modification sites, and external identifiers for the protein.

Protein Product
Y' element ATP-dependent helicase protein 1 copy 8
Feature Type
ORF , Uncharacterized
EC Number
3.6.4.12

AlphaFold Protein Structure

AlphaFold, developed by DeepMind, is an AI program that accurately predicts protein structures from amino acid sequences, enabling visualization of protein conformations. The predicted structures can be accessed through the Protein Data Bank (PDB) and AlphaFold Protein Structure Database.

Downloading... 1.00 MB

Model Confidence

Very high
Confident
Low
Very low

Experimental Data

Contains experimentally-derived protein half-life data obtained using stable isotope labeling by amino acids (SILAC) coupled with mass spectrometry. This section also contains protein abundance data for both untreated and treated cells obtained from over 20 studies. These data have been normalized and converted to a common unit of molecules per cell.

Protein Half Life

No half-life data available for YRF1-8.

Protein Abundance

Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

Abundance (molecules/cell)MediaTreatmentTreatment timeFold ChangeVisualizationStrain backgroundOriginal ReferenceReference
1133SDuntreatedconfocal microscopy evidenceS288CBreker M, et al. (2013)Ho B, et al. (2018)
535YEPDuntreatedquantitative mass spectrometry evidenceW303Nagaraj N, et al. (2012)Ho B, et al. (2018)
635SDuntreatedquantitative mass spectrometry evidenceS288CThakur SS, et al. (2011)Ho B, et al. (2018)
Showing 1 to 3 of 3 entries

Domains and Classification - S288C

Collection of computationally identified domains and motifs, as determined by InterProScan analysis; includes protein coordinates for the domain, a domain Description, a Source and corresponding accession ID, and the number of S. cerevisiae genes that share the same domain.

Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

Gene Protein Coordinates Accession ID Description Source No. of Genes with Domain

Domain Locations

Visual representation of the locations of the domains within the protein, as listed in the Domains and Classification table. Each row displays the domain(s) derived from a different Source, with domains color-coded according to this Source.

Scroll over a domain to view its exact coordinates and its Description.

Shared Domains

This diagram displays domains (colored squares) shared between the given protein (yellow circle) and other proteins (gray circles); the domains are color-coded according to their source, as displayed in the Domain Locations table, above.

Reset

Click on a gene or domain name to go to its specific page within SGD; drag any of the gene or domain objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram.

Sequence

Protein sequence for the given gene in S288C and other strains, when available. Use the pull-down menu under "Strain" to select the sequence for a specific strain. The displayed sequence can be downloaded in FASTA format as a .txt file. Amino acids displayed in blue represent modification sites. More detailed evidence for these modification sites is presented in the Post-translational Modifications table, located just below the protein sequence. 

   1 MKVSDRRKFE KANFDEFESA LNNKNDLVHC PSITLFESIP TEVRSFYEDE KSGLIKVVKF 
  61 RTGAMDRKRS FEKIVISVMV GKNVQKFLTF VEDEPDFQGG PIPSKYLIPK KINLMVYTLF 
 121 QVHTLKFNRK DYDTLSLFYL NRGYYNELSF RVLERCHEIA SARPNDSSTM RTFTDFVSGA 
 181 PIVRSLQKST IRKYGYNLAP YMFLLLHVDE LSIFSAYQAS LPGEKKVDTE RLKRDLCPRK 
 241 PIEIKYFSQI CNDMMNKKDR LGDILHIILR ACALNFGAGP RGGAGDEEDR SITNEEPIIP 
 301 SVDEHGLKVC KLRSPNTPRR LRKTLDAVKA LLVSSCACTA RDLDIFDDTN GVAMWKWIKI 
 361 LYHEVAQETT LKDSYRITLV PSSDGISVCG KLFNREYVRG FYFACKAQFD NLWGELNNCF 
 421 YMPTVVDIAS LILRNREVLF REPKRGIDEY LENDSFLQMI PVKYREIVLP KLRRDTNKMT 
 481 AALKNKVTVA IDELTVPLMW MVHFAVGYPY RYPELQLLAF AGPQRNVYVD DTTRRIQLYT 
 541 DYNKNGSSEP RLKTLDGLTS DYVFYFVTVL RQMQICALGN SYDAFNHDPW MDVVGFEDPD 
 601 QVTNRDISRI VLYSYMFLNT AKGCLVEYAT FRQYMRELPK NAPQKLNFRE MRQGLIALGR 
 661 HCVGSRFETD LYESATSELM ANHSVQTGRN IYGVDSFSLT SVSGTTATLL QERASERWIQ 
 721 WLGLESDYHC SFSSTRNAED VVAGEAASSD HDQKISRVTR KRPREPKSTN DILVAGQKLF 
 781 GSSFEFRDLH QLRLCHEIYM ADTPSVAVQA PPGYGKTELF HLPLIALASK GDVKYVSFLF 
 841 VPYTVLLANC MIRLSRCGCL NVAPVRNFIE EGCDGVTDLY VGIYDDLAST NFTDRIAAWE 
 901 NIVECTFRTN NVKLGYLIVD EFHNFETEVY RQSQFGGITN LDFDAFEKAI FLSGTAPEAV 
 961 ADAALQRIGL TGLAKKSMDI NELKRSEDLS RGLSSYPTRM FNLIKEKSEV PLGHVHKIWK 
1021 KVESQPEEAL KLLLALFEIE PESKAIVVAS TTNEVEELAC SWRKYFRVVW IHGKLGAAEK 
1081 VSRTKEFVTD GSMRVLIGTK LVTEGIDIKQ LMMVIMLDNR LNIIELIQGV GRLRDGGLCY 
1141 LLSRKNSWAA RNRKGELPPI KEGCITEQVR EFYGLESKKG KKGQHVGCCG SRTDLSADTV 
1201 ELIERMDRLA EKQATASMSI IALPSSFQES NSSDRCRKYC SSDEDSDTCI HGSANASTNA 
1261 TTNSSTNATT TASTNVRTSA TTTASINVRT SAITTESTNS STNATTTAST NVRTSATTTA 
1321 SINVRTSATT TESTNSNTSA TTTESTDSNT SATTTESTDS NTSATTTAST NSSTNATTTA 
1381 STNSSTNATT TESTNASAKE DANKDGNAED NRFHPVTDIN KESYKRKGSQ MVLLERKKLK 
1441 AQFPNTSENM NVLQFLGFRS DEIKHLFLYG IDVYFCPEGV FTQYGLCKGC QKMFELCVCW 
1501 AGQKVSYRRM AWEALAVERM LRNDEEYKEY LEDIEPYHGD PVGYLKYFSV KRGEIYSQIQ 
1561 RNYAWYLAIT RRRETISVLD STRGKQGSQV FRMSGRQIKE LYYKVWSNLR ESKTEVLQYF 
1621 LNWDEKKCRE EWEAKDDTVF VEALEKVGVF QRLRSMTSAG LQGPQYVKLQ FSRHHRQLRS 
1681 RYELSLGMHL RDQLALGVTP SKVPHWTAFL SMLIGLFYNK TFRQKLEYLL EQISEVWLLP 
1741 HWLDLANVEV LAADNTRVPL YMLMVAVHKE LDSDDVPDGR FDIILLCRDS SREVGE*

* Blue amino acids indicate modification sites. More information below.

Post-translational Modifications - S288C

Modification sites for the protein in the selected strain, based on the presence of a residue in the specific strain, as inferred from experimental evidence.

0 entries for 0 sites

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SiteModificationModifierReference
No post-translational data for this strain.
Showing 0 to 0 of 0 entries

Sequence-Based Physico-chemical Properties - S288C

Calculated protein properties, including amino acid composition, length, coding region calculations, and atomic composition.

Amino Acid Composition

Sort table using the arrow to the right of a column header to sort by that column; download all properties as a .txt file using the "Download Properties" button.

Amino AcidFrequencyPercentage
A1156.40
C362.00
D1005.57
E1256.96
F794.40
G935.18
H311.73
I874.84
K1075.96
L1699.41
M412.28
N884.90
P583.23
Q553.06
R1206.68
S1478.18
T1367.57
V1196.63
W211.17
Y693.84

Physical Details

Length (a.a): 1796
Molecular Weight (Da): 203785.1
Isoelectric Point (pl): 7.6
Formula: C9013H14213N2489O2742S77
Aliphatic Index: 76.24
Instability Index: 39.2

Coding Region Translation Calculations

Codon Bias: 0.03
Codon Adaptation Index: 0.1
Frequence of Optimal Codons: 0.45
Hydropathicity of Protein: -0.37
Aromaticity Score: 0.09

Extinction Coefficients at 280nm

ALL Cys residues appear as half cystines: 220560.0
NO Cys residues appear as half cystines: 218310.0

Atomic Composition

Sort table using the arrow to the right of a column header to sort by that column; download all properties as a .txt file using the "Download Properties" button.

Atom Frequency Percentage

Data not found or not available for  S288C

External Identifiers

List of external identifiers for the protein from various database sources.

27 entries for 7 sources

Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

External IDSource
3.6.4.12ExPASy
6320754GenBank/EMBL/DDBJ
398366399GenBank/EMBL/DDBJ
398366465GenBank/EMBL/DDBJ
Z75302GenBank/EMBL/DDBJ
U23472GenBank/EMBL/DDBJ
AAC48994.1GenBank/EMBL/DDBJ
CAA99727.1GenBank/EMBL/DDBJ
AAC48995.1GenBank/EMBL/DDBJ
338819804GenBank/EMBL/DDBJ
Showing 1 to 10 of 27 entries

Resources

Homologs

AGD | AnalogYeast | BLASTP at NCBI | BLASTP at NCBI | BLASTP at NCBI | FungiDB | PhylomeDB | YGOB | YOGY

Protein Databases

AlphaFold Protein Structure | GPMDB | ModelArchive | Pfam domains | SUPERFAMILY | TopologYeast | UniProtKB

Localization

CYCLoPs | dHITS | LoQAtE | YeastGFP | YeastRGB | YPL+

Post-translational Modifications

CoSMoS.c. | PhosphoGRID | PhosphoPep