Reference: Martegani E, et al. (1997) Identification of gene encoding a putative RNA-helicase, homologous to SKI2, in chromosome VII of Saccharomyces cerevisiae. Yeast 13(4):391-7

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Abstract


We have determined the nucleotide sequence of a segment of VII of the yeast Saccharomyces cerevisiae contained in the cosmid clone pEGH101 for a total of 7 kbp. This sequence contains a large open reading frame (ORF) called G9365, coding for a protein of 1967 amino acids that shows a significant homology with the product of the SKI2 gene of S. cerevisiae and contains domains characteristics of RNA-helicases. The ORF is transcribed in vegetative cells but it is not essential for viability as demonstrated by gene disruption.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't
Authors
Martegani E, Vanoni M, Mauri I, Rudoni S, Saliola M, Alberghina L
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